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Anna Tomascova

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Articles 11
Citations 80
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Recent Articles
1.
Lysikova T, Tomascova A, Kovalska M, Lehotsky J, Leskova Majdova K, Kaplan P, et al.
Neurol Int . 2024 May; 16(3):533-550. PMID: 38804479
It is well known that the brain is quite vulnerable to oxidative stress, initiating neuronal loss after ischemia-reperfusion (IR) injury. A potent protective mechanism is ischemic preconditioning (IPC), where proteins...
2.
Baranovicova E, Hnilicova P, Kalenska D, Kaplan P, Kovalska M, Tatarkova Z, et al.
Biomolecules . 2022 Apr; 12(4). PMID: 35454143
H Nuclear Magnetic Resonance (NMR) metabolomics is one of the fundamental tools in the fast-developing metabolomics field. It identifies and quantifies the most abundant metabolites, alterations of which can describe...
3.
Kovalska M, Baranovicova E, Kalenska D, Tomascova A, Adamkov M, Kovalska L, et al.
Int J Mol Sci . 2021 Jun; 22(9). PMID: 34066973
L-methionine, an essential amino acid, plays a critical role in cell physiology. High intake and/or dysregulation in methionine (Met) metabolism results in accumulation of its intermediate(s) or breakdown products in...
4.
Pfeiffer S, Tomascova A, Mamrak U, Haunsberger S, Connolly N, Resler A, et al.
J Neurochem . 2021 Mar; 159(4):710-728. PMID: 33694332
Progressive neuronal injury following ischaemic stroke is associated with glutamate-induced depolarization, energetic stress and activation of AMP-activated protein kinase (AMPK). We here identify a molecular signature associated with neuronal AMPK...
5.
Sivonova M, Jurecekova J, Kaplan P, Hives M, Grendar M, Tomascova A, et al.
Anticancer Res . 2020 Oct; 40(11):6257-6264. PMID: 33109563
Background/aim: The aim of this study was to evaluate the relationship between MDM2 T309G polymorphism and prostate cancer risk in the Slovak population and the association of this polymorphism with...
6.
Kovalska M, Hnilicova P, Kalenska D, Tomascova A, Adamkov M, Lehotsky J
Biomolecules . 2020 Aug; 10(8). PMID: 32751764
Hyperhomocysteinemia (hHcy) represents a strong risk factor for atherosclerosis-associated diseases, like stroke, dementia or Alzheimer's disease. A methionine (Met)-rich diet leads to an elevated level of homocysteine in plasma and...
7.
Baranovicova E, Kalenska D, Tomascova A, Holubcikova S, Lehotsky J
IUBMB Life . 2020 Jul; 72(9):2010-2023. PMID: 32663378
Cardiac arrest is one of the major causes of death and disability. The aim of the study was to identify dynamic time-dependent metabolomic changes reflected in rat plasma induced by...
8.
Tomascova A, Lehotsky J, Kalenska D, Baranovicova E, Kaplan P, Tatarkova Z
Gen Physiol Biophys . 2019 Jun; 38(4):305-314. PMID: 31219427
Blood biomarkers are usually present in low concentration and can be masked by the high-abundance proteins, of which albumin is the predominant one. The purpose of this study was to...
9.
Tothova B, Kovalska M, Kalenska D, Tomascova A, Lehotsky J
Int J Mol Sci . 2018 Oct; 19(10). PMID: 30322095
Epigenetic regulations play an important role in both normal and pathological conditions of an organism, and are influenced by various exogenous and endogenous factors. Hyperhomocysteinemia (hHcy), as a risk factor...
10.
Kovalska M, Tothova B, Kovalska L, Tatarkova Z, Kalenska D, Tomascova A, et al.
Neurochem Res . 2018 Jul; 43(9):1766-1778. PMID: 30003389
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder that results in massive hippocampal and neocortical neuronal loss leading to dementia and eventual death. The exact cause of Alzheimer's...