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Anna Lisa Palange

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Articles 18
Citations 231
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Recent Articles
1.
Moore T, Pannuzzo G, Costabile G, Palange A, Spano R, Ferreira M, et al.
Adv Drug Deliv Rev . 2023 Nov; 203:115132. PMID: 37918668
The brain remains one of the most challenging therapeutic targets due to the low and selective permeability of the blood-brain barrier and complex architecture of the brain tissue. Nanomedicines, despite...
2.
Di Mascolo D, Guerriero I, Pesce C, Spano R, Palange A, Decuzzi P
ACS Nano . 2023 Jun; 17(15):14572-14585. PMID: 37379253
Modest tissue penetrance, nonuniform distribution, and suboptimal release of drugs limit the potential of intracranial therapies against glioblastoma. Here, a conformable polymeric implant, μMESH, is realized by intercalating a micronetwork...
3.
Miali M, Chien W, Moore T, Felici A, Palange A, Oneto M, et al.
ACS Biomater Sci Eng . 2023 May; 9(6):3690-3698. PMID: 37194468
Assessing the mechanical behavior of nano- and micron-scale particles with complex shapes is fundamental in drug delivery. Although different techniques are available to quantify the bulk stiffness in static conditions,...
4.
Palange A, Di Mascolo D, Ferreira M, Gawne P, Spano R, Felici A, et al.
Adv Sci (Weinh) . 2023 Jan; 10(10):e2205223. PMID: 36683230
Breast cancer cell colonization of the lungs is associated with a dismal prognosis as the distributed nature of the disease and poor permeability of the metastatic foci challenge the therapeutic...
5.
di Francesco M, Pastorino F, Ferreira M, Fragassi A, Di Francesco V, Palange A, et al.
Pharmacol Res . 2022 Dec; 188:106639. PMID: 36586642
Neuroblastoma is a biologically heterogeneous extracranial tumor, derived from the sympathetic nervous system, that affects most often the pediatric population. Therapeutic strategies relying on aggressive chemotherapy, surgery, radiotherapy, and immunotherapy...
6.
Moore T, Cook A, Bellotti E, Palomba R, Manghnani P, Spano R, et al.
Drug Deliv Transl Res . 2022 May; 12(8):2038. PMID: 35637335
No abstract available.
7.
Felici A, Schlich M, Di Mascolo D, Goldoni L, Palange A, Decuzzi P
Eur J Pharm Biopharm . 2022 Mar; 174:90-100. PMID: 35358697
Maximizing loading while modulating the release of therapeutic molecules from nanoparticles and implantable drug delivery systems is the key to successfully address deadly diseases like brain cancer. Here, four different...
8.
Moore T, Cook A, Bellotti E, Palomba R, Manghnani P, Spano R, et al.
Drug Deliv Transl Res . 2022 Mar; 12(8):2019-2037. PMID: 35284984
The storied history of controlled the release systems has evolved over time; from degradable drug-loaded sutures to monolithic zero-ordered release devices and nano-sized drug delivery formulations. Scientists have tuned the...
9.
Palomba R, di Francesco M, Di Francesco V, Piccardi F, Catelani T, Ferreira M, et al.
Mater Horiz . 2021 Oct; 8(10):2726-2741. PMID: 34617542
Surface PEGylation, biological camouflage, shape and stiffness modulation of nanoparticles as well as liver blockade and macrophage depletion have all improved the blood longevity of nanomedicines. Yet, the mononuclear phagocytic...
10.
Di Mascolo D, Palange A, Primavera R, Macchi F, Catelani T, Piccardi F, et al.
Nat Nanotechnol . 2021 Apr; 16(7):820-829. PMID: 33795849
The poor transport of molecular and nanoscale agents through the blood-brain barrier together with tumour heterogeneity contribute to the dismal prognosis in patients with glioblastoma multiforme. Here, a biodegradable implant...