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Anna Hostalkova

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Citations 230
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Recent Articles
1.
Breiterova K, Ritomska A, Fontinha D, Kroustkova J, Suchankova D, Hostalkova A, et al.
Pharmaceutics . 2023 Mar; 15(3). PMID: 36986868
The incidence rate of malaria and the ensuing mortality prompts the development of novel antimalarial drugs. In this work, the activity of twenty-eight Amaryllidaceae alkaloids () belonging to seven different...
2.
Parvin M, Chlebek J, Hostalkova A, Catapano M, Lomozova Z, Macakova K, et al.
Molecules . 2022 Oct; 27(19). PMID: 36234964
Data on alkaloid interactions with the physiologically important transition metals, iron and copper, are mostly lacking in the literature. However, these interactions can have important consequences in the treatment of...
3.
Wijaya V, Jandourek O, Kroustkova J, Hradiska-Breiterova K, Korabecny J, Sobolova K, et al.
Biomolecules . 2022 Jun; 12(6). PMID: 35740968
Tuberculosis (TB) is a widespread infectious disease caused by . The increasing incidence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has created a need for new antiTB agents with...
4.
Vrabec R, Marikova J, Locarek M, Korabecny J, Hulcova D, Hostalkova A, et al.
Phytochemistry . 2021 Nov; 194:113017. PMID: 34798410
One undescribed indole alkaloid together with twenty-two known compounds have been isolated from aerial parts of Vinca minor L. (Apocynaceae). The chemical structures of the isolated alkaloids were determined by...
5.
Maafi N, Al Mamun A, Jandourek O, Marikova J, Breiterova K, Diepoltova A, et al.
Molecules . 2021 Oct; 26(19). PMID: 34641567
The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more...
6.
Koutova D, Kulhava M, Havelek R, Majorosova M, Kralovec K, Habartova K, et al.
Molecules . 2020 Feb; 25(4). PMID: 32093423
Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L.(Berberidaceae) plant. The results of cytotoxicity screening 48 h post-treatment showed thatbersavine considerably inhibits the proliferation and viability of...
7.
Breiterova K, Koutova D, Marikova J, Havelek R, Kunes J, Majorosova M, et al.
Plants (Basel) . 2020 Jan; 9(2). PMID: 31978967
In this detailed phytochemical study of cv. Professor Einstein, we isolated 23 previously known Amaryllidaceae alkaloids (-) of several structural types and one previously undescribed alkaloid, 7-oxonorpluviine. The chemical structures...
8.
Hulcova D, Marikova J, Korabecny J, Hostalkova A, Jun D, Kunes J, et al.
Phytochemistry . 2019 Jul; 165:112055. PMID: 31261031
Twenty-one known Amaryllidaceae alkaloids of various structural types and one undescribed alkaloid, named narcimatuline, have been isolated from fresh bulbs of Narcissus pseudonarcissus L. cv. Dutch Master. The chemical structures...
9.
Chlebek J, Korabecny J, Dolezal R, Stepankova S, Perez D, Hostalkova A, et al.
Molecules . 2019 Apr; 24(7). PMID: 30959739
In recent studies, several alkaloids acting as cholinesterase inhibitors were isolated from (Papaveraceae). Inhibitory activities of (+)-thalictricavine () and (+)-canadine () on human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were evaluated...
10.
Hostalkova A, Marikova J, Opletal L, Korabecny J, Hulcova D, Kunes J, et al.
J Nat Prod . 2019 Feb; 82(2):239-248. PMID: 30701972
Three new alkaloids, bersavine (3), muraricine (4), and berbostrejdine (8), together with seven known isoquinoline alkaloids (1-2, 5-7, 9, and 10) were isolated from an alkaloidal extract of the root...