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Anna H Bizard

Explore the profile of Anna H Bizard including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 613
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Recent Articles
11.
Sarlos K, Biebricher A, Bizard A, Bakx J, Ferrete-Bonastre A, Modesti M, et al.
Nat Struct Mol Biol . 2018 Sep; 25(9):868-876. PMID: 30177760
Faithful chromosome segregation requires that the sister chromatids be disjoined completely. Defective disjunction can lead to the persistence of histone-free threads of DNA known as ultra-fine bridges (UFBs) that connect...
12.
Martin C, Sarlos K, Logan C, Thakur R, Parry D, Bizard A, et al.
Am J Hum Genet . 2018 Jul; 103(2):221-231. PMID: 30057030
Bloom syndrome, caused by biallelic mutations in BLM, is characterized by prenatal-onset growth deficiency, short stature, an erythematous photosensitive malar rash, and increased cancer predisposition. Diagnostically, a hallmark feature is...
13.
Bizard A, Hickson I
Curr Opin Cell Biol . 2018 Mar; 52:112-119. PMID: 29525475
The anaphase of mitosis is one of the most critical stages of the cell division cycle in that it can reveal precious information on the fate of a cell lineage....
14.
Bizard A, Nielsen C, Hickson I
Methods Mol Biol . 2018 Jan; 1672:E1. PMID: 29340994
No abstract available.
15.
Bizard A, Yang X, Debat H, Fogg J, Zechiedrich L, Strick T, et al.
Nucleic Acids Res . 2017 Dec; 46(2):861-872. PMID: 29253195
DNA topoisomerases are essential enzymes involved in all the DNA processes and among them, type IA topoisomerases emerged as a key actor in the maintenance of genome stability. The hyperthermophilic...
16.
Bizard A, Nielsen C, Hickson I
Methods Mol Biol . 2017 Oct; 1672:495-508. PMID: 29043644
Ultrafine anaphase bridges (UFBs) are thin DNA threads linking the separating sister chromatids in the anaphase of mitosis. UFBs are thought to form when topological DNA entanglements between two chromatids...
17.
Pitchai G, Kaulich M, Bizard A, Mesa P, Yao Q, Sarlos K, et al.
Nucleic Acids Res . 2017 Oct; 45(19):11413-11424. PMID: 28977671
PICH is a DNA translocase required for the maintenance of chromosome stability in human cells. Recent data indicate that PICH co-operates with topoisomerase IIα to suppress pathological chromosome missegregation through...
18.
Ahuja A, Jodkowska K, Teloni F, Bizard A, Zellweger R, Herrador R, et al.
Nat Commun . 2016 Feb; 7:10660. PMID: 26876348
Embryonic stem cells (ESCs) represent a transient biological state, where pluripotency is coupled with fast proliferation. ESCs display a constitutively active DNA damage response (DDR), but its molecular determinants have...
19.
Nielsen C, Huttner D, Bizard A, Hirano S, Li T, Palmai-Pallag T, et al.
Nat Commun . 2015 Dec; 6:8962. PMID: 26643143
PICH is a SNF2 family DNA translocase that binds to ultra-fine DNA bridges (UFBs) in mitosis. Numerous roles for PICH have been proposed from protein depletion experiments, but a consensus...
20.
Newman J, Savitsky P, Allerston C, Bizard A, Ozer O, Sarlos K, et al.
Nucleic Acids Res . 2015 Apr; 43(10):5221-35. PMID: 25901030
Bloom's syndrome helicase (BLM) is a member of the RecQ family of DNA helicases, which play key roles in the maintenance of genome integrity in all organism groups. We describe...