Anna Gadek-Michalska
Overview
Explore the profile of Anna Gadek-Michalska including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
202
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Recent Articles
1.
Zelek-Molik A, Gadek-Michalska A, Wilczkowski M, Bielawski A, Maziarz K, Kreiner G, et al.
Front Pharmacol
. 2025 Jan;
15():1451895.
PMID: 39834820
Introduction: Stress-evoked dysfunctions of the frontal cortex (FC) are correlated with changes in the functioning of the glutamatergic system, and evidence demonstrates that noradrenergic transmission is an important regulator of...
2.
Zelek-Molik A, Bobula B, Gadek-Michalska A, Chorazka K, Bielawski A, Kusmierczyk J, et al.
Biomolecules
. 2021 Mar;
11(2).
PMID: 33669305
This study demonstrates how exposure to psychosocial crowding stress (CS) for 3, 7, and 14 days affects glutamate synapse functioning and signal transduction in the frontal cortex (FC) of rats....
3.
Gadek-Michalska A, Tadeusz J, Bugajski A, Bugajski J
Neurotox Res
. 2019 Jun;
36(3):523-539.
PMID: 31209786
The nitric oxide (NO) pathway in the brain is involved in response to psychosocial stressors. The aim of this study was to elucidate the role of nNOS and iNOS in...
4.
Gadek-Michalska A, Bugajski A, Tadeusz J, Rachwalska P, Bugajski J
Pharmacol Rep
. 2017 Nov;
69(6):1213-1223.
PMID: 29128802
Background: Social crowding and isolation are recognized as major stressors and risk factors for development of psychiatric disorders. Chronic isolation stress (IS) and crowding stress (CS) activate neuroendocrine and neurochemical...
5.
Kusek M, Tokarska A, Siwiec M, Gadek-Michalska A, Szewczyk B, Hess G, et al.
Front Cell Neurosci
. 2017 May;
11:127.
PMID: 28515682
Corticotropin-releasing hormone (CRH)-synthesizing parvocellular neuroendocrine cells (PNCs) of the hypothalamic paraventricular nucleus (PVN) play a key role in the activation of the hypothalamic-pituitary-adrenocortical (HPA) axis. Several studies have demonstrated that...
6.
Gadek-Michalska A, Tadeusz J, Rachwalska P, Bugajski J
Pharmacol Rep
. 2016 Sep;
68(6):1178-1196.
PMID: 27649096
Background: The aim of this study was to compare the expression of interleukin-1β (IL-1β), neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS) in the prefrontal cortex (PFC),...
7.
Gadek-Michalska A, Tadeusz J, Rachwalska P, Bugajski J
Pharmacol Rep
. 2014 Feb;
65(6):1655-62.
PMID: 24553014
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis is accepted as one of the fundamental biological mechanisms that underlie major depression. This hyperactivity is caused by diminished feedback inhibition of glucocorticoid (GC)-induced...
8.
Gadek-Michalska A, Spyrka J, Rachwalska P, Tadeusz J, Bugajski J
Pharmacol Rep
. 2014 Jan;
65(5):1163-75.
PMID: 24399712
Background: Disruption of the glucocorticoid negative feedback system evoked in animals by chronic stress can be induced by downregulation of glucocorticoid receptors (GRs) in several brain regions. In the present...
9.
Gadek-Michalska A, Tadeusz J, Rachwalska P, Spyrka J, Bugajski J
Pharmacol Rep
. 2013 Feb;
64(6):1455-65.
PMID: 23406756
Background: Interleukin-1β (IL-1β), the major cytokine involved in activation of hypothalamic-pituitary-adrenal (HPA) axis modulates both central and peripheral components regulating HPA activity. The role of nitric oxide (NO) generated by...
10.
Rogoz Z, Kabzinski M, Sadaj W, Rachwalska P, Gadek-Michalska A
Pharmacol Rep
. 2013 Feb;
64(6):1391-9.
PMID: 23406749
Background: Several clinical reports have postulated a beneficial effect of the addition of a low dose of risperidone to the ongoing treatment with antidepressants in treatment-resistant depression. Methods: The present...