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Anna Csiszar

Explore the profile of Anna Csiszar including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 262
Citations 14038
Followers 0
Related Specialties
Geriatrics
Cardiology & Vascular Diseases
Physiology
Top 10 Co-Authors
Zoltan Ungvari
Stefano Tarantini
Andriy Yabluchanskiy
William E Sonntag
Peter Toth
Tamas Kiss
Adam Nyul-Toth
Priya Balasubramanian
Peter Mukli
Tamas Csipo
Published In
Geroscience
Am J Physiol Heart Circ Physiol
J Gerontol A Biol Sci Med Sci
Aging Cell
Circ Res
Affiliations
Soon will be listed here.
Recent Articles
1.
Persisting blood-brain barrier disruption following cisplatin treatment in a mouse model of chemotherapy-associated cognitive impairment
Patai R, Csik B, Nyul-Toth A, Gulej R, Vali Kordestan K, Chandragiri S, et al.
Geroscience . 2025 Feb; PMID: 39982666
Chemotherapy-related cognitive impairment, commonly referred to as "chemobrain," significantly affects cancer survivors' quality of life, yet its underlying mechanisms remain unclear. Most chemotherapeutic agents cannot cross the blood-brain barrier (BBB),...
2.
Cisplatin and methotrexate induce brain microvascular endothelial and microglial senescence in mouse models of chemotherapy-associated cognitive impairment
Csik B, Vali Kordestan K, Gulej R, Patai R, Nyul-Toth A, Shanmugarama S, et al.
Geroscience . 2025 Feb; PMID: 39976845
The increasing number of cancer survivors has brought heightened attention to the side effects of cancer therapies, including chemotherapy-related cognitive impairment (CRCI, commonly referred to as "chemobrain"). Cisplatin and methotrexate,...
3.
Transcriptomic profiling of senescence effects on blood-brain barrier-related gene expression in brain capillary endothelial cells in a mouse model of paclitaxel-induced chemobrain
Patai R, Kiss T, Gulej R, Nyul-Toth A, Csik B, Chandragiri S, et al.
Geroscience . 2025 Feb; PMID: 39976844
Chemotherapy-induced cognitive impairment (CICI), commonly referred to as "chemobrain," is a frequent and debilitating side effect experienced by cancer survivors treated with paclitaxel (PTX). Preclinical models have shown that PTX...
4.
Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice
Natarajan D, Ekambaram S, Tarantini S, Nagaraja R, Yabluchanskiy A, Hedrick A, et al.
Aging (Albany NY) . 2025 Feb; 17(2):448-463. PMID: 39976587
Microvascular endothelial dysfunction, characterized by impaired neurovascular coupling, reduced glucose uptake, blood-brain barrier disruption, and microvascular rarefaction, plays a critical role in the pathogenesis of age-related vascular cognitive impairment (VCI)....
5.
Endothelial Colony-Forming Cells (ECFCs) in cerebrovascular aging: Focus on the pathogenesis of Vascular Cognitive Impairment and Dementia (VCID), and treatment prospects
Negri S, Reyff Z, Troyano-Rodriguez E, Milan M, Ihuoma J, Tavakol S, et al.
Ageing Res Rev . 2025 Jan; 104:102672. PMID: 39884362
Endothelial colony-forming cells (ECFCs), a unique endothelial progenitor subset, are essential for vascular integrity and repair, providing significant regenerative potential. Recent studies highlight their role in cerebrovascular aging, particularly in...
6.
COVID-19 Exacerbates Neurovascular Uncoupling and Contributes to Endothelial Dysfunction in Patients with Mild Cognitive Impairment
Owens C, Pinto C, Szarvas Z, Muranyi M, Pinaffi-Langley A, Peterfi A, et al.
Biomolecules . 2025 Jan; 14(12. PMID: 39766328
Mild cognitive impairment (MCI) affects nearly 20% of older adults worldwide, with no targetable interventions for prevention. COVID-19 adversely affects cognition, with >70% of older adults with Long COVID presenting...
7.
Sex-specific mechanisms in vascular aging: exploring cellular and molecular pathways in the pathogenesis of age-related cardiovascular and cerebrovascular diseases
Ungvari A, Gulej R, Patai R, Papp Z, Toth A, Szabo A, et al.
Geroscience . 2025 Jan; 47(1):301-337. PMID: 39754010
Aging remains the foremost risk factor for cardiovascular and cerebrovascular diseases, surpassing traditional factors in epidemiological significance. This review elucidates the cellular and molecular mechanisms underlying vascular aging, with an...
8.
Advancing prediction of age-related vascular cognitive impairment based on peripheral and retinal vascular health in a pilot study: a novel comprehensive assessment developed for a prospective workplace-based cohort (The Semmelweis Study)
Csipo T, Lipecz A, Mukli P, Peterfi A, Szarvas Z, Ungvari A, et al.
Geroscience . 2024 Nov; 47(1):1329-1344. PMID: 39604626
With a growing elderly population in the European Union, age-related diseases associated with unhealthy aging pose increasing public health challenges, including a loss of independence and heightened societal burdens. The...
9.
Energy metabolism dysregulation, cerebrovascular aging, and time-restricted eating: Current evidence and proof-of-concept findings
Pinaffi-Langley A, Pinto C, Mukli P, Peterfi A, Kaposzta Z, Owens C, et al.
PNAS Nexus . 2024 Nov; 3(11):pgae505. PMID: 39584020
Dysregulated energy metabolism is a hallmark of aging, including brain aging; thus, strategies to restore normal metabolic regulation are at the forefront of aging research. Intermittent fasting, particularly time-restricted eating...
10.
The vasoprotective role of IGF-1 signaling in the cerebral microcirculation: prevention of cerebral microhemorrhages in aging
Stankovics L, Ungvari A, Fekete M, Nyul-Toth A, Mukli P, Patai R, et al.
Geroscience . 2024 Sep; 47(1):445-455. PMID: 39271571
Aging is closely associated with various cerebrovascular pathologies that significantly impact brain function, with cerebral small vessel disease (CSVD) being a major contributor to cognitive decline in the elderly. Consequences...