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Anna C Kayani

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Articles 12
Citations 342
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Recent Articles
1.
Walton R, Jones S, Rostron K, Kayani A, Close G, McArdle A, et al.
J Gerontol A Biol Sci Med Sci . 2015 Aug; 71(8):1005-13. PMID: 26248561
With aging, there is a decline in cardiac function accompanying increasing risk of arrhythmias. These effects are likely to be mechanistically associated with age-associated changes in calcium regulation within cardiac...
2.
Zhang Y, Davis C, Sakellariou G, Shi Y, Kayani A, Pulliam D, et al.
FASEB J . 2013 Jun; 27(9):3536-48. PMID: 23729587
We have previously shown that deletion of CuZnSOD in mice (Sod1(-/-) mice) leads to accelerated loss of muscle mass and contractile force during aging. To dissect the relative roles of...
3.
Kayani A, Close G, Dillmann W, Mestril R, Jackson M, McArdle A
Am J Physiol Regul Integr Comp Physiol . 2010 Apr; 299(1):R268-76. PMID: 20410481
Skeletal muscle atrophy and weakness are major contributors to frailty and impact significantly on quality of life of older people. Muscle aging is characterized by a loss of maximum tetanic...
4.
Morton J, Kayani A, McArdle A, Drust B
Sports Med . 2009 Sep; 39(8):643-62. PMID: 19769414
Skeletal muscle adapts to the stress of contractile activity via changes in gene expression to yield an increased content of a family of highly conserved cytoprotective proteins known as heat...
5.
Kayani A, Close G, Broome C, Jackson M, McArdle A
Rejuvenation Res . 2008 Dec; 11(6):1021-30. PMID: 19086912
Unlike muscles of young mice, skeletal muscles of old mice fail to recover completely following contraction-induced damage. The mechanisms by which this occurs are not fully understood. The ability of...
6.
Morton J, Holloway K, Woods P, Cable N, Burniston J, Evans L, et al.
Muscle Nerve . 2008 Dec; 39(2):230-3. PMID: 19058194
This study investigates the effects of short-term endurance training on heat shock protein (HSP) adaptations of male and female human skeletal muscle. The data demonstrate that females did not respond...
7.
Kayani A, Morton J, McArdle A
Appl Physiol Nutr Metab . 2008 Oct; 33(5):1033-41. PMID: 18923581
Mammalian adult skeletal muscle adapts to the stress of contractile activity with increased gene expression by yielding a family of highly conserved cytoprotective proteins known as heat shock proteins (HSPs)....
8.
Morton J, MacLaren D, Cable N, Campbell I, Evans L, Kayani A, et al.
Med Sci Sports Exerc . 2008 Jun; 40(7):1255-62. PMID: 18580405
Purpose: 1) To compare the baseline levels of heat shock and antioxidant protein content in the skeletal muscle of trained and untrained humans and 2) to characterize the exercise-induced stress...
9.
Kayani A, Close G, Jackson M, McArdle A
Am J Physiol Regul Integr Comp Physiol . 2007 Nov; 294(2):R568-76. PMID: 17989141
Skeletal muscle atrophy and weakness are major causes of frailty in the elderly. Functional deficits in muscles of old humans and rodents are associated with attenuated production of heat shock...
10.
Close G, Kayani A, Ashton T, McArdle A, Jackson M
Aging Cell . 2007 Mar; 6(2):189-95. PMID: 17328687
Increased extracellular generation of reactive oxygen species (ROS) as a result of increasing reliance on glycolytic metabolism by old mitochondria-rich tissues has been claimed to contribute to the propagation of...