Anna-Karin H Ekwall
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Explore the profile of Anna-Karin H Ekwall including associated specialties, affiliations and a list of published articles.
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10
Citations
247
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Recent Articles
1.
Zhang Y, Aldridge J, Vasileiadis G, Edebo H, Ekwall A, Lundell A, et al.
Front Immunol
. 2021 Feb;
11:569883.
PMID: 33597943
Adiponectin is an adipokine with a modulatory role in metabolism and exerting both anti- and pro-inflammatory effects. Levels of adiponectin are increased in serum and synovial fluid from patients with...
2.
Aldridge J, Ekwall A, Mark L, Bergstrom B, Andersson K, Gjertsson I, et al.
Arthritis Res Ther
. 2020 Oct;
22(1):245.
PMID: 33066816
Background: The majority of CD4 T helper (Th) cells found in the synovial fluid (SF) of patients with rheumatoid arthritis (RA) express CXCR3, a receptor associated with Th1 cells. In...
3.
Svensson M, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody K, et al.
Sci Adv
. 2020 Jul;
6(26):eaba4353.
PMID: 32637608
Fibroblast-like synoviocytes (FLS) are joint-lining cells that promote rheumatoid arthritis (RA) pathology. Current disease-modifying antirheumatic agents (DMARDs) operate through systemic immunosuppression. FLS-targeted approaches could potentially be combined with DMARDs to...
4.
Bergstrom B, Lundqvist C, Vasileiadis G, Carlsten H, Ekwall O, Ekwall A
Front Immunol
. 2019 Jul;
10:1384.
PMID: 31275320
The autoimmune regulator AIRE controls the negative selection of self-reactive T-cells as well as the induction of regulatory T-cells in the thymus by mastering the transcription and presentation of tissue...
5.
Hammaker D, Whitaker J, Maeshima K, Boyle D, Ekwall A, Wang W, et al.
Arthritis Rheumatol
. 2016 May;
68(11):2637-2645.
PMID: 27159840
Objective: To identify nonobvious therapeutic targets for rheumatoid arthritis (RA), we performed an integrative analysis incorporating multiple "omics" data and the Encyclopedia of DNA Elements (ENCODE) database for potential regulatory...
6.
Ekwall A, Whitaker J, Hammaker D, Bugbee W, Wang W, Firestein G
Arthritis Rheumatol
. 2015 Feb;
67(5):1193-202.
PMID: 25707478
Objective: Fibroblast-like synoviocytes (FLS) are key players in the synovial pathology of rheumatoid arthritis (RA). Currently, there is no treatment that specifically targets these aggressive cells. By combining 3 different...
7.
Ali L, Flowers S, Jin C, Bennet E, Ekwall A, Karlsson N
Mol Cell Proteomics
. 2014 Sep;
13(12):3396-409.
PMID: 25187573
The lubricative, heavily glycosylated mucin-like synovial glycoprotein lubricin has previously been observed to contain glycosylation changes related to rheumatoid and osteoarthritis. Thus, a site-specific investigation of the glycosylation of lubricin...
8.
Svensson M, Andersson S, Erlandsson M, Jonsson I, Ekwall A, Andersson K, et al.
PLoS One
. 2013 Jan;
8(1):e54884.
PMID: 23349985
Fms-like tyrosine kinase 3 ligand (Flt3L) is known as the primary differentiation and survival factor for dendritic cells (DCs). Furthermore, Flt3L is involved in the homeostatic feedback loop between DCs...
9.
Bostrom E, Svensson M, Andersson S, Jonsson I, Ekwall A, Eisler T, et al.
Arthritis Rheum
. 2011 Jul;
63(10):2894-904.
PMID: 21739426
Objective: Human resistin has proinflammatory properties that activate NF-κB-dependent pathways, whereas its murine counterpart is associated with insulin resistance. The aim of this study was to examine potential cross-talk between...
10.
Ekwall A, Eisler T, Anderberg C, Jin C, Karlsson N, Brisslert M, et al.
Arthritis Res Ther
. 2011 Mar;
13(2):R40.
PMID: 21385358
Introduction: Activated fibroblast-like synoviocytes (FLSs) in rheumatoid arthritis (RA) share many characteristics with tumour cells and are key mediators of synovial tissue transformation and joint destruction. The glycoprotein podoplanin is...