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Anna-Karin Bostrom

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Articles 6
Citations 423
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Recent Articles
1.
Bostrom A, Lindgren D, Johansson M, Axelson H
Biochem Biophys Res Commun . 2013 Apr; 435(1):126-33. PMID: 23618868
Clear cell renal cell carcinoma (ccRCC) is by far the most common type of kidney cancer and is characterized by loss of the tumor suppressor gene von Hippel-Lindau (VHL). ccRCC...
2.
Bostrom A, Moller C, Nilsson E, Elfving P, Axelson H, Johansson M
Hum Pathol . 2011 Oct; 43(5):708-19. PMID: 21992819
Approximately 8% of clear cell renal cell carcinoma cases contain regions of radically different morphology, demonstrating a mesenchymal appearance histologically resembling sarcomas. These biphasic neoplasms are called sarcomatoid clear cell...
3.
Sjolund J, Bostrom A, Lindgren D, Manna S, Moustakas A, Ljungberg B, et al.
PLoS One . 2011 Aug; 6(8):e23057. PMID: 21826227
Background: Despite recent progress, therapy for metastatic clear cell renal cell carcinoma (CCRCC) is still inadequate. Dysregulated Notch signaling in CCRCC contributes to tumor growth, but the full spectrum of...
4.
Lindgren D, Bostrom A, Nilsson K, Hansson J, Sjolund J, Moller C, et al.
Am J Pathol . 2011 Feb; 178(2):828-37. PMID: 21281815
The tubules of the kidney display a remarkable capacity for self-renewal on damage. Whether this regeneration is mediated by dedifferentiating surviving cells or, as recently suggested, by stem cells has...
5.
Mestdagh P, Bostrom A, Impens F, Fredlund E, Van Peer G, De Antonellis P, et al.
Mol Cell . 2010 Dec; 40(5):762-73. PMID: 21145484
The miR-17-92 microRNA cluster is often activated in cancer cells, but the identity of its targets remains elusive. Using SILAC and quantitative mass spectrometry, we examined the effects of activation...
6.
Gustafsson A, Bostrom A, Ljungberg B, Axelson H, Dahlback B
PLoS One . 2009 Nov; 4(10):e7575. PMID: 19888345
Background: The molecular biology of renal cell carcinoma (RCC) is complex and not fully understood. We have recently found that the expression of the receptor tyrosine kinase Axl in the...