Ann Williams
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Explore the profile of Ann Williams including associated specialties, affiliations and a list of published articles.
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111
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2619
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Recent Articles
1.
Gate G, Williams A, Boldissar S, Sponer J, Szabla R, de Vries M
Photochem Photobiol
. 2023 Dec;
100(2):404-418.
PMID: 38124372
2,6-Diaminopurine (2,6-dAP) is an alternative nucleobase that potentially played a role in prebiotic chemistry. We studied its excited state dynamics in the gas phase by REMPI, IR-UV hole burning, and...
2.
White A, Tran A, Sibley L, Sarfas C, Morrison A, Lawrence S, et al.
Front Immunol
. 2023 Oct;
14:1246826.
PMID: 37881438
Tuberculosis remains a major health threat globally and a more effective vaccine than the current Bacillus Calmette Guerin (BCG) is required, either to replace or boost it. The Spore-FP1 mucosal...
3.
Sibley L, White A, Sarfas C, Gullick J, Gleeson F, Lanni F, et al.
Pharmaceutics
. 2022 Dec;
14(12).
PMID: 36559163
Innovative cross-over study designs were explored in non-human primate (NHP) studies to determine the value of this approach for the evaluation of drug efficacy against tuberculosis (TB). Firstly, the pharmacokinetics...
4.
Ford A, Williams A, de Vries M
Proc Natl Acad Sci U S A
. 2022 Sep;
119(40):e2121821119.
PMID: 36161917
Cacao seeds, , provide the basis for a ceremonially important Mesoamerican food. Past efforts to identify cacao in ceramics focused on highly decorative vessel forms associated with elite ceremonial contexts,...
5.
Evangelopoulos D, Shoen C, Honeyborne I, Clark S, Williams A, Mukamolova G, et al.
Microorganisms
. 2022 Feb;
10(2).
PMID: 35208914
Background: The turnaround times for phenotypic tests used to monitor the bacterial load of , in both clinical and preclinical studies, are delayed by the organism's slow growth in culture...
6.
Barber C, Syski A, Leaird J, Call R, Williams A, Learn P
Mil Med
. 2021 Dec;
PMID: 34894142
Introduction: Facing the COVID-19 pandemic, many hospitals implemented severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) screening protocols before aerosol-generating procedures (AGPs) in an effort to protect patients and health care...
7.
Schofield C, Walker T, Taylor M, Patel M, Vlachou D, Macina J, et al.
Chem Res Toxicol
. 2021 Nov;
34(12):2485-2499.
PMID: 34797640
Drug-induced liver injury is a leading cause of compound attrition during both preclinical and clinical drug development, and early strategies are in place to tackle this recurring problem. Human-relevant in...
8.
Sibley L, White A, Gooch K, Stevens L, Tanner R, Jacobs A, et al.
Sci Rep
. 2021 Jun;
11(1):12274.
PMID: 34112845
This study describes the use of cynomolgus macaques of Chinese origin (CCM) to evaluate the efficacy and immunogenicity of the BCG vaccine against high dose aerosol Mycobacterium tuberculosis challenge. Progressive...
9.
Orgeur M, Frigui W, Pawlik A, Clark S, Williams A, Ates L, et al.
Microb Genom
. 2021 Feb;
7(2).
PMID: 33529148
is an animal-adapted member of the complex (MTBC), which was originally isolated from voles, but has more recently also been isolated from other selected mammalian hosts, including occasionally from humans....
10.
Lanni F, Burton N, Harris D, Fotheringham S, Clark S, Skinner O, et al.
PLoS One
. 2021 Jan;
16(1):e0245922.
PMID: 33481939
Optimised pre-clinical models are required for TB drug development to better predict the pharmacokinetics of anti-tuberculosis (anti-TB) drugs to shorten the time taken for novel drugs and combinations to be...