Ann N Hoffman
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Explore the profile of Ann N Hoffman including associated specialties, affiliations and a list of published articles.
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30
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701
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Recent Articles
11.
Hersman S, Hoffman A, Hodgins L, Shieh S, Lam J, Parikh A, et al.
Front Neurosci
. 2019 Apr;
13:251.
PMID: 30941011
Post-traumatic stress disorder (PTSD) has a profound contextual component, and has been demonstrated to alter future contextual learning. However, the mechanism by which a single traumatic event affects subsequent contextual...
12.
Hoffman A, Taylor A
Behav Pharmacol
. 2019 Jan;
30(2 and 3-Spec Issue):115-121.
PMID: 30640181
Most people have or will experience traumatic stress at some time over the lifespan, but only a subset of traumatized individuals develop post-traumatic stress disorder (PTSD). Clinical research supports high...
13.
Hoffman A, Paode P, May H, Ortiz J, Kemmou S, Lifshitz J, et al.
J Neurotrauma
. 2016 Jun;
34(1):213-219.
PMID: 27306143
In the pathophysiology of traumatic brain injury (TBI), the amygdala remains understudied, despite involvement in processing emotional and stressful stimuli associated with anxiety disorders, such as post-traumatic stress disorder (PTSD)....
14.
Hoffman A, Parga A, Paode P, Watterson L, Nikulina E, Hammer Jr R, et al.
Neurobiol Learn Mem
. 2015 Mar;
120:61-8.
PMID: 25732249
The chronically stressed brain may present a vulnerability to develop maladaptive fear-related behaviors in response to a traumatic event. In rodents, chronic stress leads to amygdala hyperresponsivity and dendritic hypertrophy...
15.
Ortiz J, Taylor S, Hoffman A, Campbell A, Lucas L, Conrad C
Behav Brain Res
. 2015 Jan;
282:176-84.
PMID: 25591480
Chronic restraint stress alters hippocampal-dependent spatial learning and memory in a sex-dependent manner, impairing spatial performance in male rats and leaving intact or facilitating performance in female rats. Moreover, these...
16.
Ortiz J, Mathewson C, Hoffman A, Hanavan P, Terwilliger E, Conrad C
Eur J Neurosci
. 2014 Aug;
40(9):3351-62.
PMID: 25156382
Chronic restraint stress impairs hippocampal-mediated spatial learning and memory, which improves following a post-stress recovery period. Here, we investigated whether brain-derived neurotrophic factor (BDNF), a protein important for hippocampal function,...
17.
Hoffman A, Lorson N, Sanabria F, Olive M, Conrad C
Neurobiol Learn Mem
. 2014 Feb;
112:139-47.
PMID: 24508064
Chronic stress may impose a vulnerability to develop maladaptive fear-related behaviors after a traumatic event. Whereas previous work found that chronic stress impairs the acquisition and recall of extinguished fear,...
18.
Hoffman A, Anouti D, Lacagnina M, Nikulina E, Hammer Jr R, Conrad C
Stress
. 2013 May;
16(5):587-91.
PMID: 23662914
Stressors are typically multidimensional, comprised of multiple physical and sensory components that rarely occur as single isolated events. This study used a 2-day stress exposure paradigm to assess functional activation...
19.
Mika A, Mazur G, Hoffman A, Talboom J, Bimonte-Nelson H, Sanabria F, et al.
Behav Neurosci
. 2012 Aug;
126(5):605-19.
PMID: 22905921
Chronic stress leads to neurochemical and structural alterations in the prefrontal cortex (PFC) that correspond to deficits in PFC-mediated behaviors. The present study examined the effects of chronic restraint stress...
20.
Cheng J, Shaw K, Monaco C, Hoffman A, Sozda C, Olsen A, et al.
J Neurotrauma
. 2012 Jul;
29(17):2684-8.
PMID: 22774771
It is well established that a relatively brief exposure to environmental enrichment (EE) enhances motor and cognitive performance after experimental traumatic brain injury (TBI), but it is not known whether...