Ann Chen
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Explore the profile of Ann Chen including associated specialties, affiliations and a list of published articles.
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142
Citations
2796
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Recent Articles
1.
Narvaez-Bandera I, Lui A, Ayalew Mekonnen Y, Rubio V, Sulman N, Wilson C, et al.
bioRxiv
. 2024 Nov;
PMID: 39605665
Summary: The integration of metabolomics with other omics ("multi-omics") offers complementary insights into disease biology. However, this integration remains challenging due to the fragmented landscape of current methodologies, which often...
2.
Lin W, Tsui J, Chiu H, Wong W, Wu C, Hsu H, et al.
BMC Infect Dis
. 2024 Nov;
24(1):1338.
PMID: 39578786
Background: Gonorrhea, induced by Neisseria gonorrhoeae infection, stands as a prevalent sexually transmitted inflammatory disease globally. Our earlier research illuminated that N. gonorrhoeae-infected macrophages provoke inflammation by activating the intracellular...
3.
Chou Y, Chen H, Hsu B, Yang C, Chen C, Lee Y, et al.
Kidney Int
. 2024 Jul;
106(4):658-670.
PMID: 39084257
IgA nephropathy (IgAN) is the most common type of glomerulonephritis that frequently progresses to kidney failure. However, the molecular pathogenesis underlying IgAN remains largely unknown. Here, we investigated the role...
4.
Hua K, Hsu H, Huang M, Chiu H, Wong W, Peng C, et al.
J Inflamm Res
. 2024 Jun;
17:3499-3513.
PMID: 38828053
Purpose: The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, crucial in infectious and inflammatory diseases by regulating IL-1β, presents a target for disease management. causes gonorrhea in over 87...
5.
Mandula J, Sierra-Mondragon R, Jimenez R, Chang D, Mohamed E, Chang S, et al.
Immunity
. 2024 Apr;
57(5):1124-1140.e9.
PMID: 38636522
Signaling through Notch receptors intrinsically regulates tumor cell development and growth. Here, we studied the role of the Notch ligand Jagged2 on immune evasion in non-small cell lung cancer (NSCLC)....
6.
Lai J, Wu D, Wu C, Hung L, Huang C, Ka S, et al.
Sci Rep
. 2023 Nov;
13(1):20126.
PMID: 37978268
Dengue virus (DENV) infection remains a challenging health threat worldwide. Ubiquitin-specific protease 18 (USP18), which preserves the anti-interferon (IFN) effect, is an ideal target through which DENV mediates its own...
7.
Wang T, Chang F, Yang A, Ka S, Chen A, Hsieh J, et al.
PLoS One
. 2023 Jul;
18(7):e0288384.
PMID: 37471324
Aims: A subset of IgA nephropathy (IgAN) patients exhibiting minimal change disease (MCD) like features present with nephrotic-range proteinuria and warrants immunosuppressive therapy (IST). However, the diagnosis of MCD-like IgAN...
8.
Karapetyan L, Abushukair H, Li A, Knight A, Nedal Al Bzour A, MacFawn I, et al.
Front Immunol
. 2023 Jul;
14:1171978.
PMID: 37435077
Background: Proinflammatory chemokines/cytokines support development and maturation of tertiary lymphoid structures (TLS) within the tumor microenvironment (TME). In the current study, we sought to investigate the prognostic value of TLS-associated...
9.
Luhrmann T, Alderson-Day B, Chen A, Corlett P, Deeley Q, Dupuis D, et al.
Schizophr Bull
. 2023 Feb;
49(12 Suppl 2):S3-S12.
PMID: 36840538
There are communities in which hearing voices frequently is common and expected, and in which participants are not expected to have a need for care. This paper compares the ideas...
10.
Paul B, Liedtke M, Khouri J, Rifkin R, Gandhi M, Kin A, et al.
Future Oncol
. 2023 Feb;
19(1):7-17.
PMID: 36779512
Magrolimab is a monoclonal antibody that blocks CD47, a 'do not eat me' signal overexpressed on tumor cells. CD47 is overexpressed in multiple myeloma (MM), which contributes to its pathogenesis....