Ann-Christin Borchers
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Explore the profile of Ann-Christin Borchers including associated specialties, affiliations and a list of published articles.
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4
Citations
100
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Recent Articles
1.
Fullbrunn N, Nicastro R, Mari M, Griffith J, Herrmann E, Rasche R, et al.
J Cell Biol
. 2024 Mar;
223(6).
PMID: 38536036
Organelles of the endomembrane system contain Rab GTPases as identity markers. Their localization is determined by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs). It remains largely unclear...
2.
Borchers A, Janz M, Schafer J, Moeller A, Kummel D, Paululat A, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(30):e2303750120.
PMID: 37463208
Maturation from early to late endosomes depends on the exchange of their marker proteins Rab5 to Rab7. This requires Rab7 activation by its specific guanine nucleotide exchange factor (GEF) Mon1-Ccz1....
3.
Borchers A, Langemeyer L, Ungermann C
J Cell Biol
. 2021 Aug;
220(9).
PMID: 34383013
The eukaryotic endomembrane system consists of multiple interconnected organelles. Rab GTPases are organelle-specific markers that give identity to these membranes by recruiting transport and trafficking proteins. During transport processes or...
4.
Langemeyer L, Borchers A, Herrmann E, Fullbrunn N, Han Y, Perz A, et al.
Elife
. 2020 May;
9.
PMID: 32391792
Endosomes and lysosomes harbor Rab5 and Rab7 on their surface as key proteins involved in their identity, biogenesis, and fusion. Rab activation requires a guanine nucleotide exchange factor (GEF), which...