Anke Sparmann
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Explore the profile of Anke Sparmann including associated specialties, affiliations and a list of published articles.
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10
Citations
1100
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Recent Articles
1.
Vogel J, Faber F, Barquist L, Sparmann A, Popella L, Ghosh C
RNA
. 2025 Jan;
PMID: 39814459
The international symposium ASOBIOTICS 2024 brought together scientists across disciplines to discuss the challenges of advancing antibacterial antisense oligomers (ASOs) from basic research to clinical application. Hosted by the Helmholtz...
2.
Sparmann A, Vogel J
EMBO J
. 2023 Sep;
42(21):e114760.
PMID: 37728251
RNA-based therapeutics have the potential to revolutionize the treatment and prevention of human diseases. While early research faced setbacks, it established the basis for breakthroughs in RNA-based drug design that...
3.
Sparmann A, Beisel C
Mol Syst Biol
. 2022 Apr;
18(4):e11011.
PMID: 35467081
CRISPR-Cas systems allow bacteria to memorize prior infections as a means to combat the same invader if it attempts another attack in the future. While the underlying mechanisms of this...
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Sparmann A, Xie Y, Verhoeven E, Vermeulen M, Lancini C, Gargiulo G, et al.
EMBO J
. 2013 Apr;
32(11):1598-612.
PMID: 23624931
Polycomb group (PcG) proteins form transcriptional repressor complexes with well-established functions during cell-fate determination. Yet, the mechanisms underlying their regulation remain poorly understood. Here, we extend the role of Polycomb...
9.
Sparmann A, van Lohuizen M
Nat Rev Cancer
. 2006 Oct;
6(11):846-56.
PMID: 17060944
Polycomb group (PcG) proteins are epigenetic gene silencers that are implicated in neoplastic development. Their oncogenic function might be associated with their well-established role in the maintenance of embryonic and...
10.
Sparmann A, Bar-Sagi D
Cell Cycle
. 2005 May;
4(6):735-6.
PMID: 15908805
It is well established that Ras oncogenes facilitate neoplastic conversion by stimulating tumor cell growth, survival and motility. However, current studies have indicated that the role of Ras in malignant...