Anke Geng
Overview
Explore the profile of Anke Geng including associated specialties, affiliations and a list of published articles.
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15
Citations
247
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Recent Articles
1.
Wen M, Qiu Y, Wang M, Tang F, Hu W, Zhu Y, et al.
Oncogene
. 2024 Nov;
44(4):228-240.
PMID: 39516657
The effectiveness of radiotherapy in colorectal cancer (CRC) relies on its ability to induce cell death via the generation of reactive oxygen species (ROS). However, genes responsible for mitigating oxidative...
2.
Tang H, Yang J, Xu J, Zhang W, Geng A, Jiang Y, et al.
EMBO Rep
. 2024 Jun;
25(8):3263-3275.
PMID: 38866979
As a hallmark of senescent cells, the derepression of Long Interspersed Elements 1 (LINE1) transcription results in accumulated LINE1 cDNA, which triggers the secretion of the senescence-associated secretory phenotype (SASP)...
3.
Geng A, Sun J, Tang H, Yu Y, Wang X, Zhang J, et al.
Nucleic Acids Res
. 2024 Mar;
52(9):5107-5120.
PMID: 38554113
Sirtuin 2 (SIRT2) regulates the maintenance of genome integrity by targeting pathways of DNA damage response and homologous recombination repair. However, whether and how SIRT2 promotes base excision repair (BER)...
4.
Qian Z, Feng N, Geng A
Cancer Biol Ther
. 2023 Jul;
24(1):2229958.
PMID: 37408176
Hepatocellular carcinoma (HCC) is one of the most common types of malignant tumors with increasing incidence rates and high mortality rates. The currently available methods for treating HCC include surgery,...
5.
Qin N, Geng A, Xue R
Aging Dis
. 2022 Jul;
13(4):987-1004.
PMID: 35855336
As the population ages, age-related neurodegenerative diseases have become a major challenge in health science. Currently, the pathology of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis,...
6.
Geng A, Xu S, Yao Y, Qian Z, Wang X, Sun J, et al.
Cell Cycle
. 2022 Jan;
21(4):379-391.
PMID: 34985375
Chrysin, a natural compound isolated from various plants, such as the blue passion flower (.), exhibits multiple pharmacological activities, such as antitumor, anti-inflammatory and antioxidant activities. Accumulating evidence shows that...
7.
Hu Z, Cai B, Wang M, Wen X, Geng A, Hu X, et al.
Cell Cycle
. 2020 Oct;
19(22):3115-3126.
PMID: 33064975
Radiotherapy is an essential treatment for endometrial cancer (EC), especially in advanced, metastatic, and recurrent cases. Combining radiotherapy, which mainly causes DNA double-strand breaks (DSBs), with small molecules targeting aberrantly...
8.
Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(42):26356-26365.
PMID: 33020270
Understanding differences in DNA double-strand break (DSB) repair between tumor and normal tissues would provide a rationale for developing DNA repair-targeted cancer therapy. Here, using knock-in mouse models for measuring...
9.
Chen Y, Geng A, Zhang W, Qian Z, Wan X, Jiang Y, et al.
Ageing Res Rev
. 2020 Sep;
64:101154.
PMID: 32977059
DNA carries the genetic information that directs complex biological processes; thus, maintaining a stable genome is critical for individual growth and development and for human health. DNA repair is a...
10.
Geng A, Tang H, Huang J, Qian Z, Qin N, Yao Y, et al.
Nucleic Acids Res
. 2020 Aug;
48(16):9181-9194.
PMID: 32789493
The NAD+-dependent deacetylase and mono-ADP-ribosyl transferase SIRT6 stabilizes the genome by promoting DNA double strand break repair, thereby acting as a tumor suppressor. However, whether SIRT6 regulates nucleotide excision repair...