Anja Kretschmer
Overview
Explore the profile of Anja Kretschmer including associated specialties, affiliations and a list of published articles.
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17
Citations
1031
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Recent Articles
1.
Lai L, Matias-Garcia P, Kretschmer A, Gieger C, Wilson R, Linseisen J, et al.
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927065
Despite extensive research on 5-methylcytosine (5mC) in relation to smoking, there has been limited exploration into the interaction between smoking and 5-hydroxymethylcytosine (5hmC). In this study, total DNA methylation (5mC+5hmC),...
2.
Karabegovic I, Portilla-Fernandez E, Li Y, Ma J, Maas S, Sun D, et al.
Nat Commun
. 2021 May;
12(1):2830.
PMID: 33990564
Coffee and tea are extensively consumed beverages worldwide which have received considerable attention regarding health. Intake of these beverages is consistently linked to, among others, reduced risk of diabetes and...
3.
Spohn G, Witte A, Kretschmer A, Seifried E, Schafer R
Front Cell Dev Biol
. 2021 Apr;
9:638798.
PMID: 33869188
Background: Mesenchymal stromal cells (MSCs), multipotent progenitors that can be isolated from a variety of different tissues, are becoming increasingly important as cell therapeutics targeting immunopathologies and tissue regeneration. Current...
4.
Yao C, Joehanes R, Wilson R, Tanaka T, Ferrucci L, Kretschmer A, et al.
Clin Epigenetics
. 2021 Mar;
13(1):60.
PMID: 33752734
Background: DNA methylation is a key epigenetic modification that can directly affect gene regulation. DNA methylation is highly influenced by environmental factors such as cigarette smoking, which is causally related...
5.
Del C Gomez-Alonso M, Kretschmer A, Wilson R, Pfeiffer L, Karhunen V, Seppala I, et al.
Clin Epigenetics
. 2021 Jan;
13(1):7.
PMID: 33413638
Background: The discovery of robust and trans-ethnically replicated DNA methylation markers of metabolic phenotypes, has hinted at a potential role of epigenetic mechanisms in lipid metabolism. However, DNA methylation and...
6.
Schafer R, Schwab M, Siegel G, von Ameln-Mayerhofer A, Buadze M, Lourhmati A, et al.
EBioMedicine
. 2020 Sep;
60:102987.
PMID: 32942121
Background: Limited knowledge of stem cell therapies` mechanisms of action hampers their sustainable implementation into the clinic. Specifically, the interactions of transplanted stem cells with the host vasculature and its...
7.
Danielyan L, Schwab M, Siegel G, Brawek B, Garaschuk O, Asavapanumas N, et al.
EBioMedicine
. 2020 Sep;
60:102989.
PMID: 32920368
Background: Stem cells` (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the...
8.
Hertel J, Konig J, Homuth G, Van der Auwera S, Wittfeld K, Pietzner M, et al.
Sci Rep
. 2017 Oct;
7(1):14111.
PMID: 29074884
Using oral contraceptives has been implicated in the aetiology of stress-related disorders like depression. Here, we followed the hypothesis that oral contraceptives deregulate the HPA-axis by elevating circulating cortisol levels....
9.
Wilson R, Wahl S, Pfeiffer L, Ward-Caviness C, Kunze S, Kretschmer A, et al.
BMC Genomics
. 2017 Oct;
18(1):805.
PMID: 29047347
Background: The evidence for epigenome-wide associations between smoking and DNA methylation continues to grow through cross-sectional studies. However, few large-scale investigations have explored the associations using observations for individuals at...
10.
Emeny R, Baumert J, Zannas A, Kunze S, Wahl S, Iurato S, et al.
Neuropsychopharmacology
. 2017 May;
43(2):342-353.
PMID: 28540928
Epigenetic regulation in anxiety is suggested, but evidence from large studies is needed. We conducted an epigenome-wide association study (EWAS) on anxiety in a population-based cohort and validated our finding...