Anita Laitinen
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Explore the profile of Anita Laitinen including associated specialties, affiliations and a list of published articles.
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18
Citations
573
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Recent Articles
1.
Luostarinen A, Vuorela A, Kerkela E, Patrikoski M, Kotovuori A, Koski J, et al.
Sci Rep
. 2025 Mar;
15(1):8093.
PMID: 40057567
There is a growing demand for chimeric antigen receptor (CAR) -T cells for clinical trials. Consequently, new centers capable of manufacturing advanced therapy medicinal products (ATMPs) are needed. In this...
2.
Jahan F, Penna L, Luostarinen A, Veltman L, Hongisto H, Lahteenmaki K, et al.
Sci Rep
. 2024 Nov;
14(1):26678.
PMID: 39496674
Natural killer (NK) cells are a promising allogeneic immunotherapy option due to their natural ability to kill tumor cells, and due to their apparent safety. This study describes the development...
3.
Nuutila K, Katayama S, Laitinen A, Siltanen A, Patrikoski M, Valtonen J, et al.
Burns
. 2022 Oct;
49(5):1144-1156.
PMID: 36195485
Background: Autologous split-thickness skin grafts (STSGs) are the standard of care for closure of deep and large burns. However, perforation and extensive fishnet-like expansion of the grafts to achieve greater...
4.
Vijay J, Gauthier M, Biswell R, Louiselle D, Johnston J, Cheung W, et al.
Nat Metab
. 2020 Feb;
2(1):97-109.
PMID: 32066997
The complex relationship between metabolic disease risk and body fat distribution in humans involves cellular characteristics which are specific to body fat compartments. Here we show depot-specific differences in the...
5.
Salonius E, Kontturi L, Laitinen A, Haaparanta A, Korhonen M, Nystedt J, et al.
J Cell Physiol
. 2019 Sep;
235(4):3497-3507.
PMID: 31552691
Cell therapy combined with biomaterial scaffolds is used to treat cartilage defects. We hypothesized that chondrogenic differentiation bone marrow-derived mesenchymal stem cells (BM-MSCs) in three-dimensional biomaterial scaffolds would initiate cartilaginous...
6.
Oja S, Kaartinen T, Ahti M, Korhonen M, Laitinen A, Nystedt J
Front Immunol
. 2019 Aug;
10:1627.
PMID: 31379832
Some recent reports suggest that cryopreserved and thawed mesenchymal stromal cells (MSCs) may have impaired functional properties as compared to freshly harvested MSCs from continuous cultures. A cryopreservation step in...
7.
Grau-Vorster M, Laitinen A, Nystedt J, Vives J
Stem Cell Res Ther
. 2019 Jun;
10(1):164.
PMID: 31196185
Background: Contrary to the minimal criteria proposed by the International Society for Cell and Gene Therapy for defining multipotent mesenchymal stromal cells (MSC), human leukocyte antigen (HLA)-DR expression is largely...
8.
Salmenkari H, Laitinen A, Forsgard R, Holappa M, Linden J, Pasanen L, et al.
Cytotherapy
. 2019 Jan;
21(2):175-188.
PMID: 30611671
Background: Mesenchymal stromal cells (MSCs) are a promising candidate for treatment of inflammatory disorders, but their efficacy in human inflammatory bowel diseases (IBDs) has been inconsistent. Comparing the results from...
9.
Liedtke S, Sacchetti B, Laitinen A, Donsante S, Klockers R, Laitinen S, et al.
J Tissue Eng Regen Med
. 2016 May;
11(10):2725-2736.
PMID: 27214005
Effects of oxygen tension on the generation, expansion, proliferation and differentiation of stromal cell types is widely described in the literature. However, data on the internal heterogeneity of applied cell...
10.
Laitinen A, Lampinen M, Liedtke S, Kilpinen L, Kerkela E, Sarkanen J, et al.
Cytotherapy
. 2016 Feb;
18(3):423-37.
PMID: 26857232
Background Aims: Cord blood (CB) is an attractive source of mesenchymal stromal cells (MSCs) because of its abundant availability and ease of collection. However, the success rate of generating CB-MSCs...