Aniruddha C Amrite
Overview
Explore the profile of Aniruddha C Amrite including associated specialties, affiliations and a list of published articles.
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9
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347
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Recent Articles
1.
Kompella U, Amrite A, Pacha Ravi R, Durazo S
Prog Retin Eye Res
. 2013 Apr;
36:172-98.
PMID: 23603534
Treatment and management of diseases of the posterior segment of the eye such as diabetic retinopathy, retinoblastoma, retinitis pigmentosa, and choroidal neovascularization is a challenging task due to the anatomy...
2.
Cheruvu N, Amrite A, Kompella U
Pharm Res
. 2008 Nov;
26(2):404-14.
PMID: 18987961
Purpose: To investigate the effects of diabetes on transscleral retinal delivery of celecoxib in albino and pigmented rats. Methods: Albino (Sprague Dawley-SD) and pigmented (Brown Norway-BN) rats were made diabetic...
3.
Amrite A, Edelhauser H, Singh S, Kompella U
Mol Vis
. 2008 Mar;
14:150-60.
PMID: 18334929
Purpose: Our previous studies indicated that while 20 nm particles are rapidly cleared from the periocular space of the rat following posterior subconjunctival injection, 200 nm particles persisted for at...
4.
Cheruvu N, Amrite A, Kompella U
Invest Ophthalmol Vis Sci
. 2008 Jan;
49(1):333-41.
PMID: 18172110
Purpose: To determine the influence of eye pigmentation on transscleral retinal delivery of celecoxib. Methods: Melanin content in ocular tissues of both the strains was determined by sodium hydroxide solubilization...
5.
Amrite A, Edelhauser H, Kompella U
Invest Ophthalmol Vis Sci
. 2008 Jan;
49(1):320-32.
PMID: 18172109
Purpose: To develop pharmacokinetics models to describe the disposition of small lipophilic molecules in the cornea and retina after periocular (subconjunctival or posterior subconjunctival) administration. Methods: Compartmental pharmacokinetics analysis was...
6.
Amrite A, Kompella U
J Pharmacol Exp Ther
. 2007 Nov;
324(2):749-58.
PMID: 18032574
Age-related macular degeneration (ARMD) is a leading cause of blindness. The major reason for severe vision loss in ARMD is choroidal neovascularization due to an elevation in the expression of...
7.
Amrite A, Ayalasomayajula S, Cheruvu N, Kompella U
Invest Ophthalmol Vis Sci
. 2006 Mar;
47(3):1149-60.
PMID: 16505053
Purpose: To determine whether celecoxib inhibits VEGF secretion from ARPE-19 cells and to investigate further the safety and effectiveness of periocular celecoxib-poly (lactide-co-glycolide; PLGA) microparticles in inhibiting elevations in retinal...
8.
Amrite A, Kompella U
J Pharm Pharmacol
. 2005 Dec;
57(12):1555-63.
PMID: 16354399
The purpose of this study was to determine the retention and ocular distribution of subconjunctivally administered nanoparticles and microparticles. Fluorescent polystyrene particles (carboxylate modified, negatively charged) of various sizes (20...
9.
Ayalasomayajula S, Amrite A, Kompella U
Eur J Pharmacol
. 2004 Sep;
498(1-3):275-8.
PMID: 15364005
Up-regulation of cyclooxygenase-2 occurs in retinal cells during the early onset of diabetic retinopathy. Under these conditions, prostaglandin production is elevated, which in turn leads to an increased expression of...