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Angen Liu

Explore the profile of Angen Liu including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1263
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Recent Articles
1.
Kurten C, Kulkarni A, Cillo A, Santos P, Roble A, Onkar S, et al.
Nat Commun . 2021 Dec; 12(1):7338. PMID: 34921143
Head and neck squamous cell carcinoma (HNSCC) is characterized by complex relations between stromal, epithelial, and immune cells within the tumor microenvironment (TME). To enable the development of more efficacious...
2.
Ruffin A, Cillo A, Tabib T, Liu A, Onkar S, Kunning S, et al.
Nat Commun . 2021 Jun; 12(1):3349. PMID: 34099645
Current immunotherapy paradigms aim to reinvigorate CD8 T cells, but the contribution of humoral immunity to antitumor immunity remains understudied. Here, we demonstrate that in head and neck squamous cell...
3.
Zandberg D, Menk A, Velez M, Normolle D, DePeaux K, Liu A, et al.
J Immunother Cancer . 2021 May; 9(5). PMID: 33986123
The majority of patients with recurrent/metastatic squamous cell carcinoma of the head and neck (HNSCC) (R/M) do not benefit from anti-PD-1 therapy. Hypoxia induced immunosuppression may be a barrier to...
4.
Xu L, Xie X, Shi X, Zhang P, Liu A, Wang J, et al.
Oncol Lett . 2021 Mar; 21(5):353. PMID: 33747210
Sarcomas represent a heterogeneous group of mesenchymal malignancies arising at various locations in the soft tissue and bone. Though a rare disease, sarcoma affects ~200,000 patients worldwide every year. The...
5.
Zhang Y, Shi X, Zhang J, Chen X, Zhang P, Liu A, et al.
Sci Rep . 2021 Jan; 11(1):387. PMID: 33432021
Ovarian cancer is one of the most common cancers in women and is often diagnosed as advanced stage because of the subtle symptoms of early ovarian cancer. To identify the...
6.
Jiang G, Zhang W, Wang T, Ding S, Shi X, Zhang S, et al.
Jpn J Clin Oncol . 2020 Jun; 50(10):1117-1125. PMID: 32533190
Objective: Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as advanced and inoperable due to the lack of effective biomarkers and poor sensitivity of clinical diagnosis. Here, we...
7.
Tian W, Hu W, Shi X, Liu P, Ma X, Zhao W, et al.
Oncol Lett . 2020 Apr; 19(4):3101-3110. PMID: 32256810
Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as locally advanced or metastatic. Previous studies have revealed genomic characteristics of CCA in Western patients, however comprehensive genomic features...
8.
Hu J, Shang Y, Shi X, Zhang S, Shi J, Yao M, et al.
Oncol Rep . 2020 Apr; 43(6):2053-2061. PMID: 32236597
Lung cancer is the most prevalent cancer worldwide and non‑small cell lung cancer (NSCLC) is the most common subtype and accounts for 75% of all lung cancer cases. Although programmed...
9.
Cillo A, Kurten C, Tabib T, Qi Z, Onkar S, Wang T, et al.
Immunity . 2020 Jan; 52(1):183-199.e9. PMID: 31924475
Head and neck squamous cell carcinoma (HNSCC) arises through exposure to environmental carcinogens or malignant transformation by human papillomavirus (HPV). Here, we assessed the transcriptional profiles of 131,224 single cells...
10.
Rucki A, Foley K, Zhang P, Xiao Q, Kleponis J, Wu A, et al.
Cancer Res . 2016 Nov; 77(1):41-52. PMID: 27821486
Understanding how stromal signals regulate the development of pancreatic ductal adenocarcinoma (PDAC) may suggest novel therapeutic interventions in this disease. In this study, we assessed the metastatic role of stromal...