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Angelo Insola

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Recent Articles
1.
Ranieri F, Pellegrino G, Ciancio A, Musumeci G, Noce E, Insola A, et al.
J Physiol . 2021 Dec; 600(6):1497-1514. PMID: 34921406
The integration of sensory inputs in the motor cortex is crucial for dexterous movement. We recently demonstrated that a closed-loop control based on the feedback provided through intraneural multichannel electrodes...
2.
Insola A, Mazzone P, Scarnati E, Restuccia D, Valeriani M
Clin Neurophysiol . 2021 Aug; 132(10):2357-2364. PMID: 34454262
Objectives: To investigate the subcortical somatosensory evoked potentials (SEPs) to electrical stimulation of either muscle or cutaneous afferents. Methods: SEPs were recorded in 6 patients suffering from Parkinson's disease (PD)...
3.
Insola A, Mazzone P, Della Marca G, Capozzo A, Vitale F, Scarnati E
Clin Neurophysiol . 2021 Aug; 132(10):2729-2738. PMID: 34417108
Objective: To investigate the effects on the blink reflex (BR) of single stimuli applied to the pedunculopontine tegmental nucleus (PPTg). Methods: The BR was evoked by stimulating the supraorbital nerve...
4.
Lanzone J, Boscarino M, Ricci L, Insola A, Tombini M, Di Lazzaro V, et al.
Clin Neurophysiol . 2021 Mar; 132(5):1049-1056. PMID: 33743300
Objective: Wedesignedalongitudinalcohortstudyon People with Epilepsy (PwE) with the aimofassessingthe effect of Perampanel (PER) oncortico-subcortical networks, as measured by high-frequency oscillations of somatosensory evoked potentials (SEP-HFOs). SEP-HFOs measure the excitability of...
5.
Lanzone J, Boscarino M, Ricci L, Insola A, Tombini M, Di Lazzaro V, et al.
Clin Neurophysiol . 2020 Jun; 131(8):1917-1924. PMID: 32599275
Objectives: High frequency oscillations (HFOs) of Somatosensory evoked potentials (SEPs) reflect the activity of thalamo-cortical and cortical neurons from the sensory pathway. Antiepileptic-drugs (AEDs) reduce seizures acting on the balance...
6.
Assenza G, Lanzone J, Dubbioso R, Coppola A, Boscarino M, Ricci L, et al.
Clin Neurophysiol . 2020 Jun; 131(8):2041-2046. PMID: 32487476
Objectives: Juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy marked by cortical hyperexcitability. Recent neuroimaging data suggested also a thalamic role in sustaining epileptic propensity in JME. However, thalamic...
7.
Capone F, Motolese F, Rossi M, Musumeci G, Insola A, Di Lazzaro V
Mult Scler Relat Disord . 2019 Dec; 39:101897. PMID: 31869598
Background: Fatigue and fatigability are common symptoms reported by patients affected by Multiple Sclerosis (MS). The pathogenic mechanisms of such symptoms are currently unknown, but increasing evidence suggests that thalamus...
8.
Assenza G, Lanzone J, Insola A, Amatori G, Ricci L, Tombini M, et al.
Clin Neurophysiol . 2019 Dec; 131(2):548-554. PMID: 31818685
Objectives: Imaging and neurophysiological data shows that the cortical disfunction caused by focal epilepsy is not limited to the epileptic focus, thus raising the modern vision of focal epilepsy as...
9.
Insola A, Di Lazzaro V, Assenza G
Clin Neurophysiol . 2019 Feb; 130(4):439-444. PMID: 30769270
Objective: The pathophysiology of epilepsia partialis continua (EPC) is still unclear, a thalamo-cortical circuit dysfunction has been hypothesized. The aim of present study is the functional evaluation of the thalamo-cortical...
10.
Marano M, Migliore S, Squitieri F, Insola A, Scarnati E, Mazzone P
J Clin Neurosci . 2019 Jan; 62:269-272. PMID: 30612913
Tourette syndrome is a rare neuropsychiatric disorder affecting the cortico-striato-thalamo-cortical system. The disease manifests in childhood with tics and various psychiatric comorbidities. Cases of refractory Tourette syndrome are valuable candidates...