Angelika S Rambold
Overview
Explore the profile of Angelika S Rambold including associated specialties, affiliations and a list of published articles.
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26
Citations
3113
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Recent Articles
1.
Saller B, Wohrle S, Fischer L, Dufossez C, Ingerl I, Kessler S, et al.
Immunity
. 2024 Nov;
58(1):90-107.e11.
PMID: 39571574
How mitochondria reconcile roles in functionally divergent cell death pathways of apoptosis and NLRP3 inflammasome-mediated pyroptosis remains elusive, as is their precise role in NLRP3 activation and the evolutionarily conserved...
2.
Wogram E, Sumpelmann F, Dong W, Rawat E, Maestre I, Fu D, et al.
Immunity
. 2024 Aug;
57(9):2216-2231.e11.
PMID: 39151426
Microglia are the resident macrophages of the central nervous system (CNS). Their phagocytic activity is central during brain development and homeostasis-and in a plethora of brain pathologies. However, little is...
3.
Mihlan M, Wissmann S, Gavrilov A, Kaltenbach L, Britz M, Franke K, et al.
Cell
. 2024 Aug;
187(19):5316-5335.e28.
PMID: 39096902
Neutrophils are sentinel immune cells with essential roles for antimicrobial defense. Most of our knowledge on neutrophil tissue navigation derived from wounding and infection models, whereas allergic conditions remained largely...
4.
Zimmermann J, Lucht K, Stecher M, Badhan C, Glaser K, Epple M, et al.
Nat Cell Biol
. 2024 Jul;
26(8):1261-1273.
PMID: 38969763
Eukaryotic cells contain several membrane-separated organelles to compartmentalize distinct metabolic reactions. However, it has remained unclear how these organelle systems are coordinated when cells adapt metabolic pathways to support their...
5.
Glaser K, Doon-Ralls J, Walters N, Rima X, Rambold A, Reategui E, et al.
iScience
. 2024 Jan;
27(1):108656.
PMID: 38205244
Neutrophil swarming is an essential process of the neutrophil response to many pathological conditions. Resultant neutrophil accumulations are hallmarks of acute tissue inflammation and infection, but little is known about...
6.
Forde A, Kolter J, Zwicky P, Baasch S, Lohrmann F, Eckert M, et al.
Sci Immunol
. 2023 Aug;
8(86):eadg3517.
PMID: 37566679
The skin needs to balance tolerance of colonizing microflora with rapid detection of potential pathogens. Flexible response mechanisms would seem most suitable to accommodate the dynamic challenges of effective antimicrobial...
7.
Schonberger K, Mitterer M, Glaser K, Stecher M, Hobitz S, Schain-Zota D, et al.
Anal Chem
. 2023 Feb;
95(9):4325-4334.
PMID: 36812587
Metabolism plays a fundamental role in regulating cellular functions and fate decisions. Liquid chromatography-mass spectrometry (LC-MS)-based targeted metabolomic approaches provide high-resolution insights into the metabolic state of a cell. However,...
8.
Schuster E, Epple M, Glaser K, Mihlan M, Lucht K, Zimmermann J, et al.
Nat Metab
. 2022 Jul;
4(7):856-866.
PMID: 35864246
Successful elimination of bacteria in phagocytes occurs in the phago-lysosomal system, but also depends on mitochondrial pathways. Yet, how these two organelle systems communicate is largely unknown. Here we identify...
9.
Cohen S, Rambold A, Lippincott-Schwartz J
Mol Cell Oncol
. 2018 Sep;
5(5):e1043038.
PMID: 30263932
Imaging of fatty acid (FA) trafficking revealed that FAs stored in lipid droplets were delivered to mitochondria when the cells were starved. This delivery required cytoplasmic lipases and mitochondrial fusion...
10.
Rambold A, Pearce E
Trends Immunol
. 2017 Sep;
39(1):6-18.
PMID: 28923365
Immune cell differentiation and function are crucially dependent on specific metabolic programs dictated by mitochondria, including the generation of ATP from the oxidation of nutrients and supplying precursors for the...