Angela Roco
Overview
Explore the profile of Angela Roco including associated specialties, affiliations and a list of published articles.
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14
Citations
97
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Recent Articles
1.
Leal B, Torres H, Roco A, Roman R, Rojo M, Nieto E, et al.
Rev Med Chil
. 2021 Nov;
149(5):724-732.
PMID: 34751325
Background: Vitamin K antagonists such as acenocoumarol and warfarin are usually indicated for the treatment of Atrial Fibrillation (AF). The Therapeutic Range Time (TRT) is a quality of treatment indicator....
2.
Roco A, Nieto E, Suarez M, Rojo M, Bertoglia M, Veron G, et al.
Front Pharmacol
. 2020 Apr;
11:325.
PMID: 32327994
Background: Vitamin K antagonists (VKA) are used as prophylaxis for thromboembolic events in patients with cardiovascular diseases. The most common VKA are warfarin and acenocoumarol. These drugs have a narrow...
3.
Roco A, Nieto E, Quintana M, Munoz J, Ortiz V, Moreno M, et al.
Rev Med Chil
. 2020 Mar;
147(10):1273-1282.
PMID: 32186635
Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a...
4.
Roco A, Lavanderos A, Cayun J, Acevedo C, Celedon C, Rubilar J, et al.
Pharmacogenet Genomics
. 2019 May;
29(7):159-166.
PMID: 31107374
Background: Testicular cancer (TCa) is a malignant tumor with highest incidence and mortality rates in Chile. The genes coding for cytochrome P450, glutathione-S-transferases (GSTs), and UDP glucuronyl transferases (UGT) participate...
5.
Lavanderos M, Cayun J, Roco A, Sandoval C, Cerpa L, Rubilar J, et al.
Front Pharmacol
. 2019 Mar;
10:206.
PMID: 30914949
Testicular cancer is one of the most commonly occurring malignant tumors in young men with fourfold higher rate of incidence and threefold higher mortality rates in Chile than the average...
6.
Nieto E, Suarez M, Roco A, Rubilar J, Tamayo F, Rojo M, et al.
Clin Appl Thromb Hemost
. 2019 Mar;
25:1076029619834342.
PMID: 30880431
Warfarin and acenocoumarol are used in various cardiovascular disorders to improve the prognosis of patients with thromboembolic disease. However, there is a lack of substantial efficacy and safety data on...
7.
Roco A, Cerda B, Cayun J, Lavanderos A, Rubilar J, Cerro R, et al.
Rev Chil Pediatr
. 2018 Dec;
89(4):432-440.
PMID: 30571815
Cancer is the second leading cause of death in the world, causing 8.8 million deaths in 2015 according to the World Health Organization (WHO). Risk factors for cancer include smoking...
8.
Quinones L, Roco A, Cayun J, Escalante P, Miranda C, Varela N, et al.
Rev Med Chil
. 2017 Jul;
145(4):483-500.
PMID: 28748996
Pharmacogenomics is an emergent field aimed at tailoring pharmacological therapy. Genetic polymorphisms can modify the expression and function of enzymes and proteins involved in drug metabolism, affecting absorption, distribution, biotransformation...
9.
Roco A, Quinones L, Sepulveda P, Donoso H, Lapostol C, Alarcon R, et al.
Acta Cardiol
. 2015 Nov;
70(5):528-35.
PMID: 26567812
Objective: Among the genetic factors associated with cardiovascular disease (CVD), determining polymorphic genotypes could help to understand the appearance of the illness. Ethnic differences in these polymorphisms could explain population...
10.
Roco A, Cayun J, Contreras S, Stojanova J, Quinones L
Front Genet
. 2014 Dec;
5:391.
PMID: 25452763
Several recent pharmacogenetic studies have investigated the variability in both outcome and toxicity in cisplatin-based therapies. These studies have focused on the genetic variability of therapeutic targets that could affect...