Angela Midgley
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Explore the profile of Angela Midgley including associated specialties, affiliations and a list of published articles.
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20
Citations
453
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Recent Articles
1.
Zaripova L, Midgley A, Christmas S, Beresford M, Pain C, Baildam E, et al.
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003230
Mesenchymal stem cells (MSCs) modulate immune responses and maintain self-tolerance. Their trophic activities and regenerative properties make them potential immunosuppressants for treating autoimmune and autoinflammatory diseases. MSCs are drawn to...
2.
Carlsson E, Quist A, Davies J, Midgley A, Smith E, Bruce I, et al.
Clin Immunol
. 2022 Feb;
236:108948.
PMID: 35123058
Approximately 30% of adult-onset systemic lupus erythematosus (SLE) patients develop lupus nephritis (LN). The gold standard for LN detection involves renal biopsies, invasive procedures not suitable for routine disease monitoring....
3.
Zaripova L, Midgley A, Christmas S, Beresford M, Baildam E, Oldershaw R
Pediatr Rheumatol Online J
. 2021 Aug;
19(1):135.
PMID: 34425842
Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatological disorder and is classified by subtype according to International League of Associations for Rheumatology criteria. Depending on the number of...
4.
Carlsson E, Midgley A, Perkins S, Caamano-Gutierrez E, Gritzfeld J, Beresford M, et al.
Clin Immunol
. 2021 Jul;
229:108790.
PMID: 34197952
Because of their rarity, limited awareness among non-specialists, and significant overlaps in their clinical presentation, childhood autoimmune/inflammatory conditions represent a diagnostic and therapeutic challenge. Juvenile idiopathic arthritis (JIA), with its...
5.
Alnafakh R, Saretzki G, Midgley A, Flynn J, Kamal A, Dobson L, et al.
Cancers (Basel)
. 2021 Jan;
13(2).
PMID: 33450922
Dyskerin is a core-component of the telomerase holo-enzyme, which elongates telomeres. Telomerase is involved in endometrial epithelial cell proliferation. Most endometrial cancers (ECs) have high telomerase activity; however, dyskerin expression...
6.
Davies J, Carlsson E, Midgley A, Smith E, Bruce I, Beresford M, et al.
Rheumatology (Oxford)
. 2020 Dec;
60(8):3747-3759.
PMID: 33313921
Objectives: ∼30% of patients with SLE develop LN. Presence and/or severity of LN are currently assessed by renal biopsy, but biomarkers in serum or urine samples may provide an avenue...
7.
Midgley A, Barakat D, Braitch M, Nichols C, Nebozhyn M, Edwards L, et al.
Immunobiology
. 2020 Dec;
226(1):152023.
PMID: 33278709
IL-23 is a potent stimulus for Th17 cells. These cells have a distinct developmental pathway from Th1 cells induced by IL-12 and are implicated in autoimmune and inflammatory disorders including...
8.
Davies J, Midgley A, Carlsson E, Donohue S, Bruce I, Beresford M, et al.
RMD Open
. 2020 Jul;
6(2).
PMID: 32723832
Background: Approximately 30% of patients with the systemic autoimmune/inflammatory disorder systemic lupus erythematosus (SLE) develop lupus nephritis (LN) that affects treatment and prognosis. Easily accessible biomarkers do not exist to...
9.
Smith E, Lythgoe H, Midgley A, Beresford M, Hedrich C
Clin Immunol
. 2019 Nov;
209:108274.
PMID: 31678365
Juvenile-onset systemic lupus erythematosus (jSLE) accounts for up to 20% of all SLE patients. Key differences between juvenile- and adult-onset (aSLE) disease include higher disease activity, earlier development of damage,...
10.
Dimou P, Wright R, Budge K, Midgley A, Satchell S, Peak M, et al.
Sci Rep
. 2019 Jun;
9(1):8348.
PMID: 31171837
Juvenile-onset lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus erythematosus patients (JSLE). As the exact role of human renal glomerular endothelial cells (GEnCs) in LN has not...