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Angela K Lucas-Herald

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Articles 41
Citations 215
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Recent Articles
1.
Lucas-Herald A, Aksglaede L, Caspersen I, Ahmed S, Carlomagno F, Isidori A
Endocr Rev . 2025 Feb; PMID: 39932051
Klinefelter Syndrome (KS) is caused by the presence of a supernumerary X-chromosome (conferring the classical 47,XXY karyotype) and is the commonest sex chromosome abnormality in men. The clinical features described...
2.
Chai X, Lucas-Herald A, Ahmed S, Chen S, Mason A, Wong S, et al.
Clin Endocrinol (Oxf) . 2025 Jan; PMID: 39815657
Objective: Transition is important for continuity of care for patients with chronic health conditions. The aim of this service evaluation was to determine the effectiveness of a transition clinic at...
3.
Boogers L, Bruggenwirth H, Wolffenbuttel K, Hersmus R, Bryce J, Ahmed S, et al.
Eur J Endocrinol . 2025 Jan; 192(1):34-45. PMID: 39782875
Objective: 17β-Hydroxysteroid dehydrogenase 3 deficiency (17β-HSDD) and 5α-reductase type 2 deficiency (5α-RD) are rare 46,XY differences of sex development (DSD). This study aims to enlarge the limited knowledge on long-term...
4.
McGinley K, Lucas-Herald A, Connelly P, Delles C
Endocr Connect . 2024 Nov; PMID: 39585765
Background: Gender-affirming hormone therapy (GAHT) is used in individuals with gender identity dysphoria to align an individual's secondary sexual characteristics with their affirmed gender. We conducted a systematic review of...
5.
Patjamontri S, Lucas-Herald A, Bryce J, van den Akker E, Cools M, Globa E, et al.
J Clin Endocrinol Metab . 2024 Aug; PMID: 39213311
Introduction: Partial androgen insensitivity syndrome (PAIS) is a rare condition that is reported to be commonly associated with gynecomastia in males. Objectives: To assess the management of gynecomastia in male...
6.
Shaikh M, Barrett T, Bridges N, Chung R, Gevers E, Goldstone A, et al.
Endocr Connect . 2024 Jun; 13(8). PMID: 38838713
Prader-Willi syndrome (PWS) is a rare orphan disease and complex genetic neurodevelopmental disorder, with a birth incidence of approximately 1 in 10,000-30,000. Management of people with PWS requires a multi-disciplinary...
7.
Lucas-Herald A, Forbes O, McDonald H, McNeilly J, Bradley T, Wood D, et al.
Child Abuse Negl . 2024 Mar; 151:106693. PMID: 38431992
Background: In cases of fractures in children with suspicion of non-accidental injury (NAI), biochemical markers of calcium homeostasis should be performed. Objectives: To describe the pattern of biochemistry in children...
8.
Tobias E, Lucas-Herald A, Sagar D, Montezano A, Rios F, Camargo L, et al.
Endocrine . 2024 Feb; 84(2):345-349. PMID: 38400880
Purpose: Disorders/differences of sex development (DSD) result from variants in many different human genes but, frequently, have no detectable molecular cause. Methods: Detailed clinical and genetic phenotyping was conducted on...
9.
Lim M, Lucas-Herald A, Mason A, Delles C, Connelly P
J Endocrinol . 2024 Jan; 261(1). PMID: 38265843
The integral role of the hypothalamic-pituitary-gonadal axis in reproductive processes makes it a prime therapeutic target. By inhibiting sex steroid synthesis, gonadotropin-releasing hormone (GnRH) analogues are used in the management...
10.
Kuah X, Lucas-Herald A, McCarrison S, Boyle R, Adey C, Amato-Watkins A, et al.
J Neurooncol . 2024 Jan; 166(1):51-57. PMID: 38224403
Purpose: Craniopharyngiomas can be aggressive leading to significant complications and morbidity. It is not clear whether there are any predictive factors for incidence or outcomes. Our aim was therefore to...