Aneesha Bhandari
Overview
Explore the profile of Aneesha Bhandari including associated specialties, affiliations and a list of published articles.
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5
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5
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Recent Articles
1.
Deobagkar-Lele M, Crawford G, Crockford T, Back J, Hodgson R, Bhandari A, et al.
Sci Immunol
. 2024 Aug;
9(98):eadd4874.
PMID: 39121196
Dedicator of cytokinesis 8 (DOCK8) immunodeficiency syndrome is characterized by a failure of the germinal center response, a process involving the proliferation and positive selection of antigen-specific B cells. Here,...
2.
Demultiplexing of single-cell RNA-sequencing data using interindividual variation in gene expression
Nassiri I, Kwok A, Bhandari A, Bull K, Garner L, Klenerman P, et al.
Bioinform Adv
. 2024 Jun;
4(1):vbae085.
PMID: 38911824
Motivation: Pooled designs for single-cell RNA sequencing, where many cells from distinct samples are processed jointly, offer increased throughput and reduced batch variation. This study describes expression-aware demultiplexing (EAD), a...
3.
Benjamin K, Bhandari A, Kepple J, Qi R, Shang Z, Xing Y, et al.
Nature
. 2024 Jun;
630(8018):943-949.
PMID: 38898271
Spatial transcriptomics measures in situ gene expression at millions of locations within a tissue, hitherto with some trade-off between transcriptome depth, spatial resolution and sample size. Although integration of image-based...
4.
Hodgson R, Crockford T, Bhandari A, Kepple J, Back J, Cawthorne E, et al.
J Immunol
. 2023 Jan;
210(5):547-557.
PMID: 36637239
Prolidase deficiency (PD) is a multisystem disorder caused by mutations in the PEPD gene, which encodes a ubiquitously expressed metallopeptidase essential for the hydrolysis of dipeptides containing C-terminal proline or...
5.
Hodgson R, Xu X, Anzilotti C, Deobagkar-Lele M, Crockford T, Kepple J, et al.
Commun Biol
. 2022 Nov;
5(1):1216.
PMID: 36357486
Peripheral tolerance prevents the initiation of damaging immune responses by autoreactive lymphocytes. While tolerogenic mechanisms are tightly regulated by antigen-dependent and independent signals, downstream pathways are incompletely understood. N-myc downstream-regulated...