Aneesh Chandran
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Explore the profile of Aneesh Chandran including associated specialties, affiliations and a list of published articles.
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30
Citations
889
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Recent Articles
1.
Mann T, Minnies S, Gupta R, Reeve B, Nyawo G, Palmer Z, et al.
medRxiv
. 2024 Jul;
PMID: 38946942
Background: Limited data are available on the diagnostic accuracy of blood RNA biomarker signatures for extrapulmonary TB (EPTB). We addressed this question among people investigated for TB lymphadenitis and TB...
2.
Mann T, Gupta R, Reeve B, Ndlangalavu G, Chandran A, Krishna A, et al.
Lancet Glob Health
. 2024 Apr;
12(5):e783-e792.
PMID: 38583459
Background: Undiagnosed tuberculosis remains a major threat for people living with HIV. Multiple blood transcriptomic biomarkers have shown promise for tuberculosis diagnosis. We sought to evaluate their diagnostic accuracy and...
3.
Mann T, Gupta R, Reeve B, Ndlangalavu G, Chandran A, Krishna A, et al.
medRxiv
. 2023 Jul;
PMID: 37397982
Background: Undiagnosed tuberculosis (TB) remains a major threat for people living with HIV (PLHIV). Multiple blood transcriptomic biomarkers have shown promise for TB diagnosis. We sought to evaluate their diagnostic...
4.
Milighetti M, Peng Y, Tan C, Mark M, Nageswaran G, Byrne S, et al.
iScience
. 2023 Jun;
26(6):106937.
PMID: 37275518
T cell responses precede antibody and may provide early control of infection. We analyzed the clonal basis of this rapid response following SARS-COV-2 infection. We applied T cell receptor (TCR)...
5.
Devarakonda Y, Reddy M, Neethu R, Chandran A, Syal K
J Biomol Struct Dyn
. 2023 Jan;
41(22):12654-12667.
PMID: 36636838
the causative agent of sepsis, meningitis and pneumonia, is held responsible for causing invasive diseases predominantly in children along with adults from both developing and developed countries. The available vaccines...
6.
Abbott K, Salamat J, Flannery P, Chaudhury C, Chandran A, Vishveshwara S, et al.
ACS Omega
. 2022 Oct;
7(38):34034-34044.
PMID: 36188260
During multidrug combination chemotherapy, activation of the nuclear receptor and the transcription factor human pregnane xenobiotic receptor (hPXR) has been shown to play a role in the development of chemoresistance....
7.
Otter A, Abbass H, Abiodun A, Alfarih M, Alldis Z, Altmann D, et al.
Science
. 2022 Jun;
377(6603):eabq1841.
PMID: 35699621
The Omicron, or Pango lineage B.1.1.529, variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and partial neutralizing antibody (nAb) escape. Vaccinated individuals...
8.
Chee Wezen X, Chandran A, Eapen R, Waters E, Bricio-Moreno L, Tosi T, et al.
J Chem Inf Model
. 2022 May;
62(10):2586-2599.
PMID: 35533315
Lipoteichoic acid synthase (LtaS) is a key enzyme for the cell wall biosynthesis of Gram-positive bacteria. Gram-positive bacteria that lack lipoteichoic acid (LTA) exhibit impaired cell division and growth defects....
9.
Chandran A, Rosenheim J, Nageswaran G, Swadling L, Pollara G, Gupta R, et al.
Cell Rep Med
. 2022 Apr;
3(3):100557.
PMID: 35474751
Effective control of SARS-CoV-2 infection on primary exposure may reveal correlates of protective immunity to future variants, but we lack insights into immune responses before or at the time virus...
10.
Swadling L, Diniz M, Schmidt N, Amin O, Chandran A, Shaw E, et al.
Nature
. 2021 Nov;
601(7891):110-117.
PMID: 34758478
Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some individuals may clear subclinical infection before seroconversion....