Andrey A Sharov
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Explore the profile of Andrey A Sharov including associated specialties, affiliations and a list of published articles.
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28
Citations
1013
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Recent Articles
1.
Kida M, Fatima I, Rozhkova E, Otero-Vinas M, Wu M, Kalin J, et al.
J Invest Dermatol
. 2023 Aug;
144(2):378-386.e2.
PMID: 37633457
Wound healing is a complex process involving phases of hemostasis, inflammation, proliferation, and remodeling. The regenerative process in the skin requires coordination between many regulators, including signaling molecules, transcription factors,...
2.
Botchkarev V, Fessing M, Sharov A
J Invest Dermatol
. 2023 Apr;
143(7):1117-1120.
PMID: 37045617
No abstract available.
3.
Chen G, Fatima I, Xu Q, Rozhkova E, Fessing M, Mardaryev A, et al.
Sci Adv
. 2023 Jan;
9(2):eabo7605.
PMID: 36630508
Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using --driven ablation of genes in...
4.
Fatima I, Chen G, Botchkareva N, Sharov A, Thornton D, Wilkinson H, et al.
J Invest Dermatol
. 2022 Jun;
142(11):2853-2863.e4.
PMID: 35691364
Naked mole-rats (NMRs) (Heterocephalus glaber) are long-lived mammals that possess a natural resistance to cancer and other age-related pathologies, maintaining a healthy life span >30 years. In this study, using...
5.
Botchkarev V, Sharov A
J Invest Dermatol
. 2021 Sep;
142(1):12-14.
PMID: 34565558
Histone deacetylases (HDACs) induce gene repression and modify the activity of nonhistone proteins. In a new article in the Journal of Investigative Dermatology, Zhu et al. (2021) demonstrate essential roles...
6.
Poterlowicz K, Yarker J, Malashchuk I, Lajoie B, Mardaryev A, Gdula M, et al.
PLoS Genet
. 2017 Sep;
13(9):e1006966.
PMID: 28863138
Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin folding, organization of the enhancer-promoter networks and their relevance to Topologically...
7.
Rapisarda V, Malashchuk I, Asamaowei I, Poterlowicz K, Fessing M, Sharov A, et al.
J Invest Dermatol
. 2017 Jun;
137(10):2157-2167.
PMID: 28595999
The maintenance of a proper nuclear architecture and three-dimensional organization of the genes, enhancer elements, and transcription machinery plays an essential role in tissue development and regeneration. Here we show...
8.
Botchkarev V, Sharov A
J Invest Dermatol
. 2016 Feb;
136(3):557-559.
PMID: 26902124
Chemotherapy-induced hair loss is one of the most devastating side effects of cancer treatment. To study the effects of chemotherapeutic agents on the hair follicle, a number of experimental models...
9.
Mardaryev A, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, et al.
J Cell Biol
. 2015 Dec;
212(1):77-89.
PMID: 26711500
During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a...
10.
Ahmed M, Alam M, Emelianov V, Poterlowicz K, Patel A, Sharov A, et al.
J Cell Biol
. 2014 Nov;
207(4):549-67.
PMID: 25422376
Skin development is governed by complex programs of gene activation and silencing, including microRNA-dependent modulation of gene expression. Here, we show that miR-214 regulates skin morphogenesis and hair follicle (HF)...