Andrew Worlock
Overview
Explore the profile of Andrew Worlock including associated specialties, affiliations and a list of published articles.
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10
Citations
147
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Recent Articles
1.
Mwau M, Danda J, Mbugua J, Handa A, Fortunko J, Worlock A, et al.
PLoS One
. 2021 Apr;
16(4):e0249376.
PMID: 33798221
Quantification of HIV-1 RNA is essential for clinical management of HIV patients. The limited throughput and significant hands-on time required by most HIV Viral load (VL) tests makes it challenging...
2.
Bakkour S, Deng X, Bacchetti P, Grebe E, Montalvo L, Worlock A, et al.
J Clin Microbiol
. 2020 Sep;
58(12).
PMID: 32967900
Detection of residual plasma viremia in antiretroviral therapy (ART)-suppressed HIV-infected individuals is critical for characterizing the latent reservoir and evaluating the impact of cure interventions. Ultracentrifugation-based single-copy assays are sensitive...
3.
Jacobs J, Tosiano M, Koontz D, Staines B, Worlock A, Harrington K, et al.
J Clin Microbiol
. 2020 Sep;
58(12).
PMID: 32967899
Clearance of low-level viremia that persists in most HIV-1-positive individuals on antiretroviral therapy (ART) is an important milestone for efforts to cure HIV-1 infection. The level of persistent viremia on...
4.
Pham J, Meyer S, Nguyen C, Williams A, Hunsicker M, McHardy I, et al.
J Clin Microbiol
. 2020 Jul;
58(10).
PMID: 32727828
The COVID-19 pandemic caused by the new SARS-CoV-2 coronavirus has imposed severe challenges on laboratories in their effort to achieve sufficient diagnostic testing capability for identifying infected individuals. In this...
5.
Mwau M, Mbugua J, Danda J, Handa A, Worlock A, Kim H, et al.
J Clin Virol
. 2020 Feb;
125:104289.
PMID: 32097889
Background: Early infant diagnosis (EID) of HIV-1 exposed infants enables timely initiation of antiretroviral therapy (ART), thereby allowing early diagnosis and treatment to slow disease progression and reduce mortality. Turn-around...
6.
Yek C, Massanella M, Peling T, Lednovich K, Nair S, Worlock A, et al.
J Clin Microbiol
. 2017 Jun;
55(8):2544-2553.
PMID: 28592548
The search for a cure for HIV infection has highlighted the need for increasingly sensitive and precise assays to measure viral burden in various tissues and body fluids. We describe...
7.
Manak M, Hack H, Nair S, Worlock A, Malia J, Peel S, et al.
J Clin Microbiol
. 2016 Aug;
54(10):2575-81.
PMID: 27510829
Quantitation of the HIV-1 viral load in plasma is the current standard of care for clinical monitoring of HIV-infected individuals undergoing antiretroviral therapy. This study evaluated the analytical and clinical...
8.
Norris P, Zhang J, Worlock A, Nair S, Anastos K, Minkoff H, et al.
Open Forum Infect Dis
. 2016 Mar;
3(1):ofw025.
PMID: 26966697
Background. Subjects on suppressive combination antiretroviral therapy (cART) who do not achieve robust reconstitution of CD4(+) T cells face higher risk of complications and death. We studied participants in the...
9.
Nair S, Kim H, Fortunko J, Foote T, Peling T, Tran C, et al.
J Clin Virol
. 2016 Feb;
77:46-54.
PMID: 26896710
Background: Separate assays are available for diagnosis and viral load (VL) monitoring of HIV-1. Studies have shown that using a single test for both confirmatory diagnosis and VL increases linkage...
10.
Rook M, Delach S, Deyneko G, Worlock A, Wolfe J
Am J Pathol
. 2003 Dec;
164(1):23-33.
PMID: 14695315
Genome-wide screening of genetic alterations between normal and cancer cells, as well as among subgroups of tumors, is important for establishing molecular mechanism and classification of cancer. Gene silencing through...