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Andrew T Miller

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Articles 31
Citations 740
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Recent Articles
1.
Chiang C, Lane D, Zou Y, Hoffman T, Pan J, Hampton J, et al.
Front Microbiol . 2022 Apr; 13:803041. PMID: 35369443
Current therapies for anthrax include the use of antibiotics (i.e., doxycycline, and ciprofloxacin), an anthrax vaccine (BioThrax) and -specific, monoclonal antibody (mAb) (i.e., Raxibacumab and obiltoxaximab). In this study, we...
2.
Bickhaus J, Fraser M, Weidner A, Jayes F, Amundsen C, Gall K, et al.
Female Pelvic Med Reconstr Surg . 2020 Oct; 27(2):e469-e475. PMID: 33105344
Objective: Polycarbonate urethane (PCU) is a new biomaterial, and its mechanical properties can be tailored to match that of vaginal tissue. We aimed to determine whether vaginal host immune and...
3.
Thangavelu G, Du J, Paz K, Loschi M, Zaiken M, Flynn R, et al.
Blood . 2019 Nov; 135(1):28-40. PMID: 31697815
T-cell activation releases inositol 1,4,5-trisphosphate (IP3), inducing cytoplasmic calcium (Ca2+) influx. In turn, inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) phosphorylates IP3 to negatively regulate and thereby tightly control Ca2+ fluxes that...
4.
Korolowizc K, Li B, Huang X, Yon C, Rodrigo E, Corpuz M, et al.
Hepatol Commun . 2019 Oct; 3(10):1296-1310. PMID: 31592075
Current therapeutics for chronic infection with hepatitis B virus (HBV) rarely induce functional cure due to the immunotolerant status of patients. Small molecule agonists targeting toll-like receptor 7 (TLR7) have...
5.
Lodaya R, Brito L, Wu T, Miller A, Otten G, Singh M, et al.
J Pharm Sci . 2018 Jun; 107(9):2310-2314. PMID: 29883663
Adjuvants are required to enhance immune responses to typically poorly immunogenic recombinant antigens. Toll-like receptor agonists (TLRa) have been widely evaluated as adjuvants because they activate the innate immune system....
6.
Kelly C, Miller A, Hollister S, Guldberg R, Gall K
Adv Healthc Mater . 2017 Dec; 7(7):e1701095. PMID: 29280325
3D printing is now adopted for use in a variety of industries and functions. In biomedical engineering, 3D printing has prevailed over more traditional manufacturing methods in tissue engineering due...
7.
Miller A, Safranski D, Wood C, Guldberg R, Gall K
J Mech Behav Biomed Mater . 2017 Jul; 75:1-13. PMID: 28689135
Polyurethane (PU) based elastomers continue to gain popularity in a variety of biomedical applications as compliant implant materials. In parallel, advancements in additive manufacturing continue to provide new opportunities for...
8.
Locci M, Wu J, Arumemi F, Mikulski Z, Dahlberg C, Miller A, et al.
Nat Immunol . 2016 Sep; 17(10):1235. PMID: 27648551
No abstract available.
9.
Locci M, Wu J, Arumemi F, Mikulski Z, Dahlberg C, Miller A, et al.
Nat Immunol . 2016 Jul; 17(8):976-84. PMID: 27376469
Follicular helper T cells (TFH cells) are CD4(+) T cells specialized in helping B cells and are associated both with protective antibody responses and autoimmune diseases. The promise of targeting...
10.
Cortez A, Li Y, Miller A, Zhang X, Yue K, Maginnis J, et al.
J Med Chem . 2016 Jun; 59(12):5868-78. PMID: 27270029
Small molecule Toll-like receptor 7 (TLR7) agonists have been used as vaccine adjuvants by enhancing innate immune activation to afford better adaptive response. Localized TLR7 agonists without systemic exposure can...