Andrew T Koppisch
Overview
Explore the profile of Andrew T Koppisch including associated specialties, affiliations and a list of published articles.
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27
Citations
469
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Recent Articles
1.
Bardsley T, Evans C, Greene J, Audet R, Harrison M, Zimmerman M, et al.
J Biomed Mater Res B Appl Biomater
. 2020 Dec;
109(9):1271-1282.
PMID: 33373104
Wound healing attempts to maintain homeostasis in the wound while minimizing the risk of infection to the tissue by foreign agents, such as opportunistic bacterial pathogens. Biofilms established by these...
2.
Greene J, Merrett K, Heyert A, Simmons L, Migliori C, Vogt K, et al.
PLoS One
. 2019 Sep;
14(9):e0222211.
PMID: 31527873
Choline geranate (also described as Choline And GEranic acid, or CAGE) has been developed as a novel biocompatible antiseptic material capable of penetrating skin and aiding the transdermal delivery of...
3.
Bartee D, Sanders S, Phillips P, Harrison M, Koppisch A, Freel Meyers C
ACS Infect Dis
. 2019 Jan;
5(3):406-417.
PMID: 30614674
To fight the growing threat of antibiotic resistance, new antibiotics are required that target essential bacterial processes other than protein, DNA/RNA, and cell wall synthesis, which constitute the majority of...
4.
Sanders S, Bartee D, Harrison M, Phillips P, Koppisch A, Freel Meyers C
PLoS One
. 2018 May;
13(5):e0197638.
PMID: 29771999
The in vivo microenvironment of bacterial pathogens is often characterized by nutrient limitation. Consequently, conventional rich in vitro culture conditions used widely to evaluate antibacterial agents are often poorly predictive...
5.
Sanders S, Vierling R, Bartee D, DeColli A, Harrison M, Aklinski J, et al.
ACS Infect Dis
. 2017 Jun;
3(7):467-478.
PMID: 28636325
1-Deoxy-d-xylulose 5-phosphate (DXP) synthase catalyzes the thiamin diphosphate (ThDP)-dependent formation of DXP from pyruvate and d-glyceraldehyde 3-phosphate. DXP is at a metabolic branch point in bacteria, feeding into the methylerythritol...
6.
Browne D, Jenkins J, Schmutz J, Shu S, Barry K, Grimwood J, et al.
Genome Announc
. 2017 Apr;
5(16).
PMID: 28428306
has long been known as a prodigious producer of liquid hydrocarbon oils that can be converted into combustion engine fuels. This draft genome for the B race of will allow...
7.
Harrington L, Jha R, Kern T, Schmidt E, Canales G, Finney K, et al.
ACS Synth Biol
. 2016 Aug;
6(1):120-129.
PMID: 27548779
Thermostabilization of an enzyme with complete retention of catalytic efficiency was demonstrated on recombinant 3-dehydroshikimate dehydratase (DHSase or wtAsbF) from Bacillus thuringiensis serovar konkukian 97-27 (hereafter, B. thuringiensis 97-27). The...
8.
Zakrewsky M, Banerjee A, Apte S, Kern T, Jones M, Del Sesto R, et al.
Adv Healthc Mater
. 2016 Mar;
5(11):1282-9.
PMID: 26959835
Antiseptic agents are the primary arsenal to disinfect skin and prevent pathogens spreading within the host as well as into the surroundings; however the Food and Drug Administration published a...
9.
Zakrewsky M, Lovejoy K, Kern T, Miller T, Le V, Nagy A, et al.
Proc Natl Acad Sci U S A
. 2014 Aug;
111(37):13313-8.
PMID: 25157174
Biofilm-protected microbial infections in skin are a serious health risk that remains to be adequately addressed. The lack of progress in developing effective treatment strategies is largely due to the...
10.
Jarchow-Choy S, Koppisch A, Fox D
Curr Org Chem
. 2014 Jul;
18(8):1050-1072.
PMID: 25009443
Isoprenoids constitute the largest class of natural products with greater than 55,000 identified members. They play essential roles in maintaining proper cellular function leading to maintenance of human health, plant...