Andrew Spencer
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Explore the profile of Andrew Spencer including associated specialties, affiliations and a list of published articles.
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258
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9747
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Recent Articles
11.
Irving A, Petrie D, Harris A, Fanning L, Wood E, Moore E, et al.
PLoS One
. 2024 Aug;
19(8):e0308812.
PMID: 39190684
Multiple myeloma is a haematological malignancy typically characterised by neoplastic plasma cell infiltration of the bone marrow. Treatment for multiple myeloma consists of multi-line chemotherapy with or without autologous stem...
12.
Tan J, Curtis D, Muirhead J, Swain M, Fleming S, Cirone B, et al.
Clin Lymphoma Myeloma Leuk
. 2024 Aug;
24(11):e852-e860.
PMID: 39181858
Background: Regular monitoring of CD34 donor chimerism (DC) is a highly sensitive method of predicting relapse in allogeneic stem cell transplant (alloHSCT) recipients with AML/MDS. A fall of CD34 DC...
13.
Chai K, Wellard C, Thao L, Aoki N, Moore E, Augustson B, et al.
EJHaem
. 2024 Aug;
5(4):690-697.
PMID: 39157592
Serious infection is common in patients with multiple myeloma due to immune deficiency from the underlying disease and/or its treatment. Immunoglobulin replacement is one approach to reduce infection risk in...
14.
Tan J, Barmanray R, Cirone B, Klarica D, Russell A, Spencer A, et al.
Transplant Cell Ther
. 2024 Jul;
30(10):970-985.
PMID: 39053769
Advances in allogeneic hematopoietic stem cell transplantation (alloHSCT) and supportive care over the past decade have reduced transplant and relapse-related mortality, leading to a greater number of long-term survivors. However,...
15.
Ho P, Moore E, Wellard C, Quach H, Blacklock H, Harrrison S, et al.
Br J Haematol
. 2024 Jul;
205(4):1337-1345.
PMID: 38965706
A decade after International Myeloma Working Group (IMWG) biomarkers (SLiM criteria) were introduced, this real-world study examined their impact on diagnosis, therapy and outcomes in myeloma. Using the ANZ MRDR,...
16.
Mollee P, Reynolds J, Janowski W, Quach H, Campbell P, Gibbs S, et al.
Blood Adv
. 2024 May;
8(14):3721-3730.
PMID: 38739707
In newly diagnosed transplant-ineligible patients with myeloma, daratumumab has improved outcomes when added to the standard-of-care regimens. In a randomized trial, we tested whether similar improvements would be observed when...
17.
Ho P, Spencer A, Mollee P, Bryant C, Enjeti A, Horvath N, et al.
Clin Lymphoma Myeloma Leuk
. 2024 May;
24(8):543-552.e1.
PMID: 38702217
Background And Purpose: Renal impairment (RI) confers adverse prognosis in myeloma; its reversal and avoidance of dialysis are crucial. We investigated whether serum free light chain (SFLC) measurements can predict...
18.
Aoki N, Chen P, Chen W, Chng W, Gan G, Goh Y, et al.
BMC Med Res Methodol
. 2024 May;
24(1):102.
PMID: 38698331
Background: Multiple myeloma (MM) is the second most common haematological cancer worldwide. Along with related diseases including monoclonal gammopathy of undetermined significance (MGUS), plasma cell leukaemia (PCL) and plasmacytoma, MM...
19.
Minnie S, Waltner O, Zhang P, Takahashi S, Nemychenkov N, Ensbey K, et al.
Sci Immunol
. 2024 Apr;
9(94):eadg1094.
PMID: 38640253
Chronic antigen stimulation is thought to generate dysfunctional CD8 T cells. Here, we identify a CD8 T cell subset in the bone marrow tumor microenvironment that, despite an apparent terminally...
20.
Zeissig M, Hewett D, Mrozik K, Panagopoulos V, Wallington-Gates C, Spencer A, et al.
Leuk Res
. 2024 Mar;
139:107469.
PMID: 38479337
Background: The proteasome inhibitor bortezomib is one of the primary therapies used for the haematological malignancy multiple myeloma (MM). However, intrinsic or acquired resistance to bortezomib, via mechanisms that are...