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Andrew S Lang

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Articles 106
Citations 2307
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Recent Articles
11.
Alkie T, Byrne A, Jones M, Mollett B, Bourque L, Lung O, et al.
Viruses . 2023 Sep; 15(9). PMID: 37766243
In December 2022 and January 2023, we isolated clade 2.3.4.4b H5N1 high-pathogenicity avian influenza (HPAI) viruses from six American crows () from Prince Edward Island and a red fox ()...
12.
Alim N, Koppenhofer S, Lang A, Beatty J
Genes (Basel) . 2023 May; 14(5). PMID: 37239483
A variety of prokaryotes produce a bacteriophage-like gene transfer agent (GTA), and the alphaproteobacterial RcGTA is a model GTA. Some environmental isolates of lack the ability to acquire genes transferred...
13.
Langille E, Bottaro C, Lang A
Phage (New Rochelle) . 2023 Feb; 3(4):194-203. PMID: 36793882
Background: Gene transfer agents (GTAs) are phage-like particles that transfer cellular genomic DNA between cells. A hurdle faced in studying GTA function and interactions with cells is the difficulty in...
14.
Canuti M, Rodrigues B, Lang A, Dufour S, Verhoeven J
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36613573
Metagenomic methods are powerful tools to investigate viral diversity in biological or environmental samples and to identify previously unknown viruses. We used RNA metagenomics to identify, in the gut of...
15.
Koppenhofer S, Lang A
BMC Genomics . 2022 Dec; 23(1):834. PMID: 36522693
Background: Bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) is a bacterial second messenger that affects diverse processes in different bacteria, including the cell cycle, motility, and biofilm formation. Its cellular levels are...
16.
Canuti M, Wilson L, Bowes V, Redford T, Dufour S, Lang A, et al.
Curr Res Microb Sci . 2022 Dec; 3:100169. PMID: 36518169
Caliciviruses are ssRNA viruses that can infect a wide range of hosts, including birds. While several avian caliciviruses have been discovered, their taxonomy and host distribution are largely unknown. We...
17.
Canuti M, Rodrigues B, Bouchard E, Whitney H, Lang A, Dufour S, et al.
Curr Res Microb Sci . 2022 Dec; 3:100161. PMID: 36518163
Circoviruses (genus , family ) are ssDNA viruses that infect mammals, and they sometimes can transmit among different species. We investigated the distribution and diversity of porcine circovirus 3 (PCV-3,...
18.
Kogay R, Koppenhofer S, Beatty J, Kuhn J, Lang A, Zhaxybayeva O
Virus Evol . 2022 Nov; 8(2):veac100. PMID: 36381234
Morphological and genetic features strongly suggest that gene transfer agents (GTAs) are caudoviricete-derived entities that have evolved in concert with cellular genomes to such a degree that they should not...
19.
Koppenhofer S, Tomasch J, Lang A
Microb Genom . 2022 Nov; 8(11). PMID: 36350115
Gene transfer agents (GTAs) are phage-like particles that transfer pieces of cellular genomic DNA to other cells. Homologues of the GTA (RcGTA) structural genes are widely distributed in the Alphaproteobacteria...
20.
Lang A
PLoS Biol . 2022 Nov; 20(11):e3001874. PMID: 36346786
The potential benefits of producing gene transfer agents (GTAs) have long been speculated. A new study in PLOS Biology shows that DNA transfer by these phage-like elements allows cells with...