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Andrew S Islam

Explore the profile of Andrew S Islam including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Islam A, Beidelschies M, Huml A, Greenfield E
J Orthop Res . 2010 Sep; 29(2):211-7. PMID: 20806319
Adherent pathogen-associated molecular patterns (PAMPs) act through toll-like receptor 2 (TLR2) and TLR4 to increase the biological activity of orthopedic wear particles in cell culture and animal models of implant...
2.
Beidelschies M, Huang H, McMullen M, Smith M, Islam A, Goldberg V, et al.
J Cell Physiol . 2008 Jul; 217(3):652-66. PMID: 18651635
Bone loss that causes aseptic loosening of orthopedic implants is initiated by pro-inflammatory cytokines produced by macrophages in response to implant-derived wear particles. MAPK and NF-kappaB signaling pathways are activated...
3.
Smith M, Lee M, Islam A, Rohrer J, Goldberg V, Beidelschies M, et al.
J Bone Joint Surg Am . 2007 May; 89(5):1019-27. PMID: 17473139
Background: Wear debris contributes to implant loosening after total joint arthroplasty, and few advances have been made in our ability to inhibit the biological response to wear particles. Bacterial endotoxins...
4.
Tatro J, Taki N, Islam A, Goldberg V, Rimnac C, Doerschuk C, et al.
J Orthop Res . 2006 Nov; 25(3):361-9. PMID: 17106883
Bacterial endotoxin may contribute to aseptic loosening of orthopedic implants even in the absence of clinical or microbiological evidence of infection. One potential source of endotoxin during aseptic loosening is...