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Andrew Rawstron

Explore the profile of Andrew Rawstron including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 167
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Recent Articles
1.
Munir T, Cairns D, Bloor A, Allsup D, Cwynarski K, Pettitt A, et al.
N Engl J Med . 2023 Dec; 390(4):326-337. PMID: 38078508
Background: The combination of ibrutinib and venetoclax has been shown to improve outcomes in patients with chronic lymphocytic leukemia (CLL) as compared with chemoimmunotherapy. Whether ibrutinib-venetoclax and personalization of treatment...
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Hillmen P, Pitchford A, Bloor A, Broom A, Young M, Kennedy B, et al.
Lancet Oncol . 2023 May; 24(5):535-552. PMID: 37142374
Background: The approval of Bruton tyrosine kinase (BTK) inhibitors in patients with previously untreated chronic lymphocytic leukaemia (CLL) was based on trials which compared ibrutinib with alkylating agents in patients...
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Wierda W, Rawstron A, Cymbalista F, Badoux X, Rossi D, Brown J, et al.
Leukemia . 2021 Jun; 35(11):3059-3072. PMID: 34168283
Assessment of measurable residual disease (often referred to as "minimal residual disease") has emerged as a highly sensitive indicator of disease burden during and at the end of treatment and...
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Pepper A, Zucchetto A, Norris K, Tissino E, Polesel J, Soe Z, et al.
Leukemia . 2021 Jun; 36(1):271-274. PMID: 34148055
No abstract available.
6.
Lamb M, Smith A, Painter D, Kane E, Bagguley T, Newton R, et al.
BMJ Open . 2021 Feb; 11(2):e041296. PMID: 33619185
Objective: To examine mortality and morbidity patterns before and after premalignancy diagnosis in individuals with monoclonal gammopathy of undetermined significance (MGUS) and monoclonal B-cell lymphocytosis (MBL) and compare their secondary...
7.
Appleby N, Eyre T, Cabes M, Jackson A, Boucher R, Yates F, et al.
BMC Cancer . 2019 May; 19(1):471. PMID: 31109313
Background: Transformation of chronic lymphocytic leukaemia (CLL) to diffuse large B-cell lymphoma (DLCBL) type Richter's syndrome (RS) carries a dismal prognosis. Standard-of-care chemoimmunotherapy for de novo RS is inadequate with...
8.
Norris K, Hillmen P, Rawstron A, Hills R, Baird D, Fegan C, et al.
Leukemia . 2019 Feb; 33(8):1953-1963. PMID: 30700843
We have previously shown that dividing patients with CLL into those with telomeres inside the fusogenic range (TL-IFR) and outside the fusogenic range (TL-OFR) is powerful prognostic tool. Here, we...
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Richardson S, Khan I, Rawstron A, Sudak J, Edwards N, Verfuerth S, et al.
Br J Haematol . 2013 Jan; 160(5):640-8. PMID: 23293871
Following reduced intensity-conditioned allogeneic stem cell transplantation (RIC allo-SCT) for chronic lymphocytic leukaemia (CLL), there is an inverse relationship between relapse and extensive chronic graft-versus-host disease (GVHD). We evaluated outcomes...
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Pettitt A, Jackson R, Carruthers S, Dodd J, Dodd S, Oates M, et al.
J Clin Oncol . 2012 Apr; 30(14):1647-55. PMID: 22493413
Purpose: In chronic lymphocytic leukemia (CLL), TP53 deletion/mutation is strongly associated with an adverse outcome and resistance to chemotherapy-based treatment. In contrast, TP53 defects are not associated with resistance to...