Andrew R Harris
Overview
Explore the profile of Andrew R Harris including associated specialties, affiliations and a list of published articles.
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24
Citations
1321
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0
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Recent Articles
11.
Fozouni P, Son S, de Leon Derby M, Knott G, Gray C, DAmbrosio M, et al.
Cell
. 2020 Dec;
184(2):323-333.e9.
PMID: 33306959
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an ongoing global pandemic due in part to the challenge of identifying symptomatic, asymptomatic, and pre-symptomatic carriers of...
12.
Harris A, Jreij P, Belardi B, Joffe A, Bausch A, Fletcher D
Nat Commun
. 2020 Nov;
11(1):5973.
PMID: 33239610
The assembly of actin filaments into distinct cytoskeletal structures plays a critical role in cell physiology, but how proteins localize differentially to these structures within a shared cytoplasm remains unclear....
13.
Belardi B, Hamkins-Indik T, Harris A, Kim J, Xu K, Fletcher D
Dev Cell
. 2020 Aug;
54(6):792-804.e7.
PMID: 32841596
In vertebrates, epithelial permeability is regulated by the tight junction (TJ) formed by specialized adhesive membrane proteins, adaptor proteins, and the actin cytoskeleton. Despite the TJ's critical physiological role, a...
14.
Harris A, Belardi B, Jreij P, Wei K, Shams H, Bausch A, et al.
Mol Biol Cell
. 2019 Nov;
30(26):3112-3122.
PMID: 31693446
Tandem calponin homology (CH1-CH2) domains are common actin-binding domains in proteins that interact with and organize the actin cytoskeleton. Despite regions of high sequence similarity, CH1-CH2 domains can have remarkably...
15.
Wyatt T, Harris A, Lam M, Cheng Q, Bellis J, Dimitracopoulos A, et al.
Proc Natl Acad Sci U S A
. 2015 Apr;
112(18):5726-31.
PMID: 25908119
Cell division plays an important role in animal tissue morphogenesis, which depends, critically, on the orientation of divisions. In isolated adherent cells, the orientation of mitotic spindles is sensitive to...
16.
Moeendarbary E, Harris A
Wiley Interdiscip Rev Syst Biol Med
. 2014 Oct;
6(5):371-88.
PMID: 25269160
Cells generate and sustain mechanical forces within their environment as part of their normal physiology. They are active materials that can detect mechanical stimulation by the activation of mechanosensitive signaling...
17.
Harris A, Daeden A, Charras G
J Cell Sci
. 2014 Mar;
127(Pt 11):2507-17.
PMID: 24659804
Adherens junctions and desmosomes integrate the cytoskeletons of adjacent cells into a mechanical syncitium. In doing so, intercellular junctions endow tissues with the strength needed to withstand the mechanical stresses...
18.
Harris A, Bellis J, Khalilgharibi N, Wyatt T, Baum B, Kabla A, et al.
Nat Protoc
. 2013 Nov;
8(12):2516-30.
PMID: 24263091
Cell monolayers line most of the surfaces and cavities in the human body. During development and normal physiology, monolayers sustain, detect and generate mechanical stresses, yet little is known about...
19.
Moeendarbary E, Valon L, Fritzsche M, Harris A, Moulding D, Thrasher A, et al.
Nat Mater
. 2013 Jan;
12(3):253-61.
PMID: 23291707
The cytoplasm is the largest part of the cell by volume and hence its rheology sets the rate at which cellular shape changes can occur. Recent experimental evidence suggests that...
20.
Terry S, Elbediwy A, Zihni C, Harris A, Bailly M, Charras G, et al.
PLoS One
. 2012 Nov;
7(11):e50188.
PMID: 23185572
Actinomyosin activity is an important driver of cell locomotion and has been shown to promote collective cell migration of epithelial sheets as well as single cell migration and tumor cell...