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Andrew McGovern

Explore the profile of Andrew McGovern including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 879
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Recent Articles
1.
Harid A, Rowe M, Patel N, Jeffery J, Flanagan D, McGovern A
Endocr Pract . 2025 Mar; PMID: 40049331
Objective: To identify a morning cortisol threshold value which confirms non-recovery of the adrenal axis and therefore negates the need for a Short Synacthen test (SST) in those with known...
2.
Raina K, Forbes C, Stronk R, Rappi Jr J, Eastman K, Zaware N, et al.
Cell Chem Biol . 2024 Aug; 31(8):1490-1502.e42. PMID: 39116881
We describe a protein proximity inducing therapeutic modality called Regulated Induced Proximity Targeting Chimeras or RIPTACs: heterobifunctional small molecules that elicit a stable ternary complex between a target protein (TP)...
3.
Tobias D, Merino J, Ahmad A, Aiken C, Benham J, Bodhini D, et al.
Nat Med . 2023 Oct; 29(10):2438-2457. PMID: 37794253
Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds...
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Lynam A, Curtis C, Stanley B, Heatley H, Worthington C, Roberts E, et al.
Pragmat Obs Res . 2023 May; 14:39-49. PMID: 37138785
Introduction: Electronic medical records (EMRs) maintained in primary care in the UK and collected and stored in EMR databases offer a world-leading resource for observational clinical research. We aimed to...
6.
Raina K, Forbes C, Stronk R, Rappi Jr J, Eastman K, Gerritz S, et al.
bioRxiv . 2023 Jan; PMID: 36711980
While specific cell signaling pathway inhibitors have yielded great success in oncology, directly triggering cancer cell death is one of the great drug discovery challenges facing biomedical research in the...
7.
Thomas N, McGovern A, Young K, Sharp S, Weedon M, Hattersley A, et al.
J Clin Epidemiol . 2022 Nov; 153:34-44. PMID: 36368478
Objectives: We aimed to compare the performance of approaches for classifying insulin-treated diabetes within research datasets without measured classification biomarkers, evaluated against two independent biological definitions of diabetes type. Study...
8.
de Lusignan S, McGovern A, Hinton W, Whyte M, Munro N, Williams E, et al.
Diabetes Ther . 2022 Sep; 13(10):1789-1809. PMID: 36050586
Introduction: Initiation of injectable therapies in type 2 diabetes (T2D) is often delayed, however the reasons why are not fully understood. Methods: A mixed methods study performed in sequential phases....
9.
de Lusignan S, Alexander H, Broderick C, Dennis J, McGovern A, Feeney C, et al.
J Allergy Clin Immunol . 2022 Apr; 150(3):709-713. PMID: 35469843
Background: Atopic dermatitis (AD) is associated with immune dysregulation, but epidemiologic data on the pattern of autoimmune comorbidity in people with AD are limited. Objective: We sought to determine the...
10.
Whyte M, Joy M, Hinton W, McGovern A, Hoang U, van Vlymen J, et al.
Diabetes Obes Metab . 2022 Apr; 24(7):1310-1318. PMID: 35373891
Aim: To determine whether achieving early glycaemic control, and any subsequent glycaemic variability, was associated with any change in the risk of major adverse cardiovascular events (MACE). Materials And Methods:...