Andrew MacWilliams
Overview
Explore the profile of Andrew MacWilliams including associated specialties, affiliations and a list of published articles.
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7
Citations
1595
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Recent Articles
1.
Wanamaker S, Garza R, MacWilliams A, Nery J, Bartlett A, Castanon R, et al.
Nat Methods
. 2023 Jan;
20(3):469.
PMID: 36690743
No abstract available.
2.
Luck K, Kim D, Lambourne L, Spirohn K, Begg B, Bian W, et al.
Nature
. 2020 Apr;
580(7803):402-408.
PMID: 32296183
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships. Here we present a human 'all-by-all' reference interactome map of human...
3.
Wanamaker S, Garza R, MacWilliams A, Nery J, Bartlett A, Castanon R, et al.
Nat Methods
. 2017 Jun;
14(8):819-825.
PMID: 28650476
Broad-scale protein-protein interaction mapping is a major challenge given the cost, time, and sensitivity constraints of existing technologies. Here, we present a massively multiplexed yeast two-hybrid method, CrY2H-seq, which uses...
4.
Zhong Q, Pevzner S, Hao T, Wang Y, Mosca R, Menche J, et al.
Mol Syst Biol
. 2016 Apr;
12(4):865.
PMID: 27107014
In cellular systems, biophysical interactions between macromolecules underlie a complex web of functional interactions. How biophysical and functional networks are coordinated, whether all biophysical interactions correspond to functional interactions, and...
5.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman G, Hao T, Richardson A, et al.
Cell
. 2016 Feb;
164(4):805-17.
PMID: 26871637
While alternative splicing is known to diversify the functional characteristics of some genes, the extent to which protein isoforms globally contribute to functional complexity on a proteomic scale remains unknown....
6.
Rolland T, Tasan M, Charloteaux B, Pevzner S, Zhong Q, Sahni N, et al.
Cell
. 2014 Nov;
159(5):1212-1226.
PMID: 25416956
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality...
7.
Reece-Hoyes J, Barutcu A, McCord R, Jeong J, Jiang L, MacWilliams A, et al.
Nat Methods
. 2011 Nov;
8(12):1050-2.
PMID: 22037702
Gateway-compatible yeast one-hybrid (Y1H) assays provide a convenient gene-centered (DNA to protein) approach to identify transcription factors that can bind a DNA sequence of interest. We present Y1H resources, including...