Andrew Macklin
Overview
Explore the profile of Andrew Macklin including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
351
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0
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Recent Articles
1.
Gruber R, Wirak G, Blazier A, Lee L, Dufault M, Hagan N, et al.
Nat Commun
. 2024 Nov;
15(1):10116.
PMID: 39578444
Neuroinflammation in the central nervous system (CNS), driven largely by resident phagocytes, has been proposed as a significant contributor to disability accumulation in multiple sclerosis (MS) but has not been...
2.
Cheong A, Craciun F, Husson H, Gans J, Escobedo J, Chang Y, et al.
Commun Biol
. 2024 Aug;
7(1):932.
PMID: 39095617
While significant advances have been made in understanding renal pathophysiology, less is known about the role of glycosphingolipid (GSL) metabolism in driving organ dysfunction. Here, we used a small molecule...
3.
Khoo A, Govindarajan M, Qiu Z, Liu L, Ignatchenko V, Waas M, et al.
Nat Commun
. 2024 Jun;
15(1):5069.
PMID: 38871730
Urine is a complex biofluid that reflects both overall physiologic state and the state of the genitourinary tissues through which it passes. It contains both secreted proteins and proteins encapsulated...
4.
Bakhshinyan D, Suk Y, Kuhlmann L, Adile A, Ignatchenko V, Custers S, et al.
Acta Neuropathol Commun
. 2023 Oct;
11(1):169.
PMID: 37872586
No abstract available.
5.
Khoo A, Govindarajan M, Qiu Z, Liu L, Ignatchenko V, Waas M, et al.
bioRxiv
. 2023 Aug;
PMID: 37546794
Urine is a complex biofluid that reflects both overall physiologic state and the state of the genitourinary tissues through which it passes. It contains both secreted proteins and proteins encapsulated...
6.
Bakhshinyan D, Suk Y, Kuhlmann L, Adile A, Ignatchenko V, Custers S, et al.
Acta Neuropathol Commun
. 2023 Jul;
11(1):111.
PMID: 37430373
Medulloblastoma (MB) is the most common type of malignant pediatric brain cancer. The current standard of care (SOC) involves maximal safe resection and chemoradiotherapy in individuals older than 3 years,...
7.
Qazi M, Salim S, Brown K, Mikolajewicz N, Savage N, Han H, et al.
Cell Rep
. 2022 Sep;
40(13):111420.
PMID: 36170831
Recurrence of solid tumors renders patients vulnerable to advanced, treatment-refractory disease state with mutational and oncogenic landscape distinctive from initial diagnosis. Improving outcomes for recurrent cancers requires a better understanding...
8.
Grunwald B, Devisme A, Andrieux G, Vyas F, Aliar K, McCloskey C, et al.
Cell
. 2021 Oct;
184(22):5577-5592.e18.
PMID: 34644529
Intratumoral heterogeneity is a critical frontier in understanding how the tumor microenvironment (TME) propels malignant progression. Here, we deconvolute the human pancreatic TME through large-scale integration of histology-guided regional multiOMICs...
9.
Kurganovs N, Wang H, Huang X, Ignatchenko V, Macklin A, Khan S, et al.
Proteomics Clin Appl
. 2021 Jun;
15(5):e2100037.
PMID: 34152685
To model the problem of radiation resistance in prostate cancer, cell lines mimicking a clinical course of conventionally fractionated or hypofractionated radiotherapy have been generated. Proteomic analysis of radiation resistant...
10.
Dashora U, Gregory R, Winocour P, Dhatariya K, Rowles S, Macklin A, et al.
Clin Med (Lond)
. 2021 May;
21(3):204-210.
PMID: 34001571
Sodium glucose co-transporter 2 (SGLT2) inhibitors are now an established class of medications for the treatment of type 2 diabetes (T2D), no longer reserved for use by specialists in diabetes....