Andrew Karaplis
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Explore the profile of Andrew Karaplis including associated specialties, affiliations and a list of published articles.
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26
Citations
354
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Recent Articles
1.
Kritzinger J, Wyse J, Karaplis A
BMJ Case Rep
. 2024 Dec;
17(12).
PMID: 39694647
Serum calcium and phosphorus levels are tightly regulated by the calciotropic hormone parathyroid hormone, fibroblast growth factor 23 and 1,25(OH) vitamin D. Commonly prescribed therapies for iron-deficiency anaemia (IDA) such...
2.
Zhu Q, Zhou X, Zhu M, Wang Q, Goltzman D, Karaplis A, et al.
J Bone Miner Res
. 2018 Dec;
33(12):2239-2241.
PMID: 30521118
No abstract available.
3.
Zhang Y, Chen G, Gu Z, Sun H, Karaplis A, Goltzman D, et al.
Int J Biol Sci
. 2018 May;
14(5):508-517.
PMID: 29805302
We previously demonstrated that parathyroid hormone-related peptide (PTHrP) 1-84 knockin ( KI) mice, which lacked a PTHrP nuclear localization sequence (NLS) and C-terminus, displayed early senescence, defective osteoblastic bone formation,...
4.
Camirand A, Goltzman D, Gupta A, Kaouass M, Panda D, Karaplis A
PLoS One
. 2016 Jul;
11(7):e0160034.
PMID: 27463808
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients, but with an accelerated timeframe. This rapid effect on weight-bearing bones is also...
5.
Zhou X, Dai X, Wu X, Ji J, Karaplis A, Goltzman D, et al.
Sci Rep
. 2016 Jul;
6:29171.
PMID: 27373231
To investigate whether overexpression of Bmi1 in lymphocytes can stimulate skeletogenesis by improving the osteogenic microenvironment, we examined the skeletal phenotype of EμBmi1 transgenic mice with overexpression of Bmi1 in...
6.
Sun W, Wu J, Huang L, Liu H, Wang R, Karaplis A, et al.
Endocrinology
. 2016 Feb;
157(4):1372-84.
PMID: 26859332
To determine whether the action of the PTHrP nuclear localization sequence and C terminus is mediated through p27 in modulating dental and mandibular development, compound mutant mice, which are homozygous...
7.
Jiang M, Chen G, Lu N, Zhang Y, Jin S, Karaplis A, et al.
Exp Dermatol
. 2015 Jun;
24(11):847-52.
PMID: 26121068
We previously reported that deficiency of the PTHrP nuclear localization sequence (NLS) and C-terminus in PTHrP knockin (PTHrP KI) mice resulted in premature ageing of skin. P27, a cyclin-dependent kinase...
8.
Zhu M, Zhang J, Dong Z, Zhang Y, Wang R, Karaplis A, et al.
J Bone Miner Res
. 2015 Apr;
30(11):1969-79.
PMID: 25917430
Parathyroid hormone-related peptide (PTHrP) 1-84 knock-in mice (Pthrp KI) develop skeletal growth retardation and defective osteoblastic bone formation. To further examine the mechanisms underlying this phenotype, microarray analyses of differential...
9.
Boras-Granic K, Dann P, VanHouten J, Karaplis A, Wysolmerski J
PLoS One
. 2014 May;
9(5):e90418.
PMID: 24785493
Parathyroid hormone-related protein (PTHrP) can be secreted from cells and interact with its receptor, the Type 1 PTH/PTHrP Receptor (PTHR1) in an autocrine, paracrine or endocrine fashion. PTHrP can also...
10.
Bisphosphonates for treatment of osteoporosis: expected benefits, potential harms, and drug holidays
Brown J, Morin S, Leslie W, Papaioannou A, Cheung A, Davison K, et al.
Can Fam Physician
. 2014 Apr;
60(4):324-33.
PMID: 24733321
Objective: To outline the efficacy and risks of bisphosphonate therapy for the management of osteoporosis and describe which patients might be eligible for bisphosphonate "drug holiday." Quality Of Evidence: MEDLINE...