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Andrew Jirasek

Explore the profile of Andrew Jirasek including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 228
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Recent Articles
1.
Kunkyab T, Magliari A, Jirasek A, Mou B, Hyde D
J Appl Clin Med Phys . 2024 Aug; 25(11):e14489. PMID: 39186819
Purpose: To evaluate the feasibility of an open-source, semi-automated, and reproducible vertex placement tool to improve the efficiency of lattice radiotherapy (LRT) planning. We used polymer gel dosimetry with a...
2.
Kunkyab T, Lakrad K, Jirasek A, Oldham M, Quinn B, Hyde D, et al.
Phys Med Biol . 2024 Jul; 69(15). PMID: 38959910
To develop and benchmark a novel 3D dose verification technique consisting of polymer gel dosimetry (PGD) with cone-beam-CT (CBCT) readout through a two-institution study. The technique has potential for wide...
3.
Wiebe M, Milligan K, Brewer J, Fuentes A, Ali-Adeeb R, Brolo A, et al.
Analyst . 2024 Apr; 149(10):2864-2876. PMID: 38619825
Radiation-induced lung injury (RILI) is a dose-limiting toxicity for cancer patients receiving thoracic radiotherapy. As such, it is important to characterize metabolic associations with the early and late stages of...
4.
Collins S, Ogilvy A, Hare W, Hilts M, Jirasek A
Biomed Phys Eng Express . 2024 Apr; 10(3). PMID: 38579691
Modern radiation therapy technologies aim to enhance radiation dose precision to the tumor and utilize hypofractionated treatment regimens. Verifying the dose distributions associated with these advanced radiation therapy treatments remains...
5.
Fuentes A, Milligan K, Wiebe M, Narayan A, Lum J, Brolo A, et al.
Analyst . 2024 Feb; 149(5):1645-1657. PMID: 38312026
Reprogramming of cellular metabolism is a driving factor of tumour progression and radiation therapy resistance. Identifying biochemical signatures associated with tumour radioresistance may assist with the development of targeted treatment...
6.
Collins S, Ogilvy A, Huang D, Hare W, Hilts M, Jirasek A
Med Phys . 2023 May; 50(10):6334-6353. PMID: 37190786
Background: Gel dosimeters are a potential tool for measuring the complex dose distributions that characterize modern radiotherapy. A prototype tabletop solid-tank fan-beam optical CT scanner for readout of gel dosimeters...
7.
Hill I, Boyd M, Milligan K, Jenkins C, Sorensen A, Jirasek A, et al.
Analyst . 2023 May; 148(11):2594-2608. PMID: 37166147
Radiation therapy is currently utilised in the treatment of approximately 50% of cancer patients. A move towards patient tailored radiation therapy would help to improve the treatment outcome for patients...
8.
Kunkyab T, Mou B, Jirasek A, Haston C, Andrews J, Thomas S, et al.
Phys Med Biol . 2023 May; 68(16). PMID: 37164024
. The development of radiation-induced fibrosis after stereotactic ablative radiotherapy (SABR) can obscure follow-up images and delay detection of a local recurrence in early-stage lung cancer patients. The objective of...
9.
Milligan K, Scarrott K, Andrews J, Brolo A, Lum J, Jirasek A
Appl Spectrosc . 2023 Apr; 77(7):698-709. PMID: 37097829
Raman spectroscopy is a useful tool for obtaining biochemical information from biological samples. However, interpretation of Raman spectroscopy data in order to draw meaningful conclusions related to the biochemical make...
10.
Fuentes A, Narayan A, Milligan K, Lum J, Brolo A, Andrews J, et al.
Sci Rep . 2023 Jan; 13(1):1530. PMID: 36707535
Tumour cells exhibit altered metabolic pathways that lead to radiation resistance and disease progression. Raman spectroscopy (RS) is a label-free optical modality that can monitor post-irradiation biomolecular signatures in tumour...