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Andrew J Putnam

Explore the profile of Andrew J Putnam including associated specialties, affiliations and a list of published articles. Areas
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Articles 94
Citations 3736
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Recent Articles
1.
Zhang I, Choi L, Friend N, McCoy A, Midekssa F, Alsberg E, et al.
bioRxiv . 2024 Nov; PMID: 39605682
The development of perfusable and multiscale vascular networks remains one of the largest challenges in tissue engineering. As such, there is a need for the creation of customizable and facile...
2.
Margolis E, Choi L, Friend N, Putnam A
Sci Rep . 2024 Feb; 14(1):4036. PMID: 38369633
Strategies to separately manufacture arterial-scale tissue engineered vascular grafts and microvascular networks have been well-established, but efforts to bridge these two length scales to create hierarchical vasculature capable of supporting...
3.
Ky A, McCoy A, Flesher C, Friend N, Li J, Akinleye K, et al.
Adipocyte . 2023 Oct; 12(1):2268261. PMID: 37815174
Alterations of the extracellular matrix contribute to adipose tissue dysfunction in metabolic disease. We studied the role of matrix density in regulating human adipocyte phenotype in a tunable hydrogel culture...
4.
Hobson E, Li W, Friend N, Putnam A, Stegemann J, Deng C
Biomaterials . 2023 Sep; 302:122282. PMID: 37672999
Viscoelastic properties of hydrogels are important for their application in science and industry. However, rheological assessment of soft hydrogel biomaterials is challenging due to their complex, rapid, and often time-dependent...
5.
Friend N, Beamish J, Margolis E, Schott N, Stegemann J, Putnam A
J Biomed Mater Res A . 2023 Jun; 112(4):549-561. PMID: 37326361
There is a significant clinical need to develop effective vascularization strategies for tissue engineering and the treatment of ischemic pathologies. In patients afflicted with critical limb ischemia, comorbidities may limit...
6.
Margolis E, Friend N, Rolle M, Alsberg E, Putnam A
Trends Biotechnol . 2023 May; 41(11):1400-1416. PMID: 37169690
In human vascular anatomy, blood flows from the heart to organs and tissues through a hierarchical vascular tree, comprising large arteries that branch into arterioles and further into capillaries, where...
7.
Aliabouzar M, Quesada C, Chan Z, Fowlkes J, Franceschi R, Putnam A, et al.
Acta Biomater . 2023 Apr; 164:195-208. PMID: 37121372
Microporosity in hydrogels is critical for directing tissue formation and function. We have developed a fibrin-based smart hydrogel, termed an acoustically responsive scaffold (ARS), which responds to focused ultrasound in...
8.
Friend N, McCoy A, Stegemann J, Putnam A
Biomaterials . 2023 Feb; 295:122050. PMID: 36812843
The formation of functional capillary blood vessels that can sustain the metabolic demands of transplanted parenchymal cells remains one of the biggest challenges to the clinical realization of engineered tissues...
9.
Aliabouzar M, Ley A, Meurs S, Putnam A, Baker B, Kripfgans O, et al.
Bioprinting . 2022 Jan; 25. PMID: 35087958
Acoustically-responsive scaffolds (ARSs) are composite hydrogels that respond to ultrasound in an on-demand, spatiotemporally-controlled manner due to the presence of a phase-shift emulsion. When exposed to ultrasound, a gas bubble...
10.
Zou D, Vigen M, Putnam A, Cao C, Tarle S, Guinn T, et al.
Cell Tissue Res . 2022 Jan; 388(1):75-88. PMID: 35028747
Mesenchymal stem cells (MSCs) have broad-based therapeutic potential in regenerative medicine. However, a major barrier to their clinical utility is that MSCs from different tissues are highly variable in their...