Andrew J Nichols
Overview
Explore the profile of Andrew J Nichols including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
51
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Recent Articles
1.
Subudhi A, Evero O, Reitinger J, Davis C, Gronewold J, Nichols A, et al.
Exp Physiol
. 2020 May;
106(1):117-125.
PMID: 32363610
New Findings: What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute...
2.
Zimmer M, Bista P, Benson E, Lee D, Liu F, Picarella D, et al.
Hepatol Commun
. 2018 Feb;
1(4):311-325.
PMID: 29404461
CAT-2003 is a novel conjugate of eicosapentaenoic acid (EPA) and niacin designed to be hydrolyzed by fatty acid amide hydrolase to release EPA inside cells at the endoplasmic reticulum. In...
3.
Vu C, Bridges R, Pena-Rasgado C, Lacerda A, Bordwell C, Sewell A, et al.
J Med Chem
. 2016 Dec;
60(1):458-473.
PMID: 27976892
A depressed autophagy has previously been reported in cystic fibrosis patients with the common F508del-CFTR mutation. This report describes the synthesis and preliminary biological characterization of a novel series of...
4.
Vu C, Bemis J, Benson E, Bista P, Carney D, Fahrner R, et al.
J Med Chem
. 2016 Jan;
59(3):1217-31.
PMID: 26784936
This report describes the synthesis and preliminary biological characterization of novel fatty acid niacin conjugates and fatty acid salicylate conjugates. These molecular entities were created by covalently linking two bioactive...
5.
Noh H, Hu Y, Park T, DiCioccio T, Nichols A, Okajima K, et al.
J Pharmacol Exp Ther
. 2008 Nov;
328(2):496-503.
PMID: 18974362
Aldose reductase (AR), an enzyme widely believed to be involved in the aberrant metabolism of glucose and development of diabetic complications, is expressed at low levels in the mouse. We...
6.
Hong S, Lubben T, Dolliver C, Petrolonis A, Roy R, Li Z, et al.
Bioorg Chem
. 2005 Jan;
33(1):34-44.
PMID: 15668181
Mitogen-activated protein kinase phosphatase-4 (MKP-4) is a dual specificity phosphatase, which acts as a negative regulator of insulin-stimulated pathways. Here, we describe expression, purification, and biochemical characterization of MKP-4. We...