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Andrew J Kennedy

Explore the profile of Andrew J Kennedy including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 538
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Recent Articles
1.
Haridas R, Cooper M, Kennedy A
Anaesth Intensive Care . 2025 Jan; 310057X241285171. PMID: 39866034
The acquisition of an early ether inhaler stimulated research into several inhalers classified as Bruck inhalers. Ludwig Hermann Bruck was a German migrant who arrived in Australia in 1873. He...
2.
Thompson A, Ferguson M, Kearney G, Kennedy A, Kubeil L, Macleay C, et al.
Animals (Basel) . 2024 Mar; 14(6). PMID: 38539967
Ewe lambs that are heavier due to improved nutrition pre- and post-weaning achieve puberty at a younger age, are more fertile, and have a higher reproductive rate. Fatness is intimately...
3.
Kim H, Gao E, Draper A, Berens N, Vihma H, Zhang X, et al.
Elife . 2022 May; 11. PMID: 35535852
Pitt-Hopkins syndrome (PTHS) is a neurodevelopmental disorder caused by monoallelic mutation or deletion in the () gene. Individuals with PTHS typically present in the first year of life with developmental...
4.
Cheema M, Good K, Kim B, Soufari H, OSullivan C, Freeman M, et al.
Cells . 2020 May; 9(5). PMID: 32397240
The replication independent (RI) histone H2A.Z is one of the more extensively studied variant members of the core histone H2A family, which consists of many replication dependent (RD) members. The...
5.
Poplawski S, Garbett K, McMahan R, Kordasiewicz H, Zhao H, Kennedy A, et al.
Mol Ther Nucleic Acids . 2020 Mar; 19:1399-1412. PMID: 32160709
Knockout of the memory suppressor gene histone deacetylase 2 (Hdac2) in mice elicits cognitive enhancement, and drugs that block HDAC2 have potential as therapeutics for disorders affecting memory. Currently available...
6.
Phan B, Bohlen J, Davis B, Ye Z, Chen H, Mayfield B, et al.
Nat Neurosci . 2020 Feb; 23(3):375-385. PMID: 32015540
Autism spectrum disorder (ASD) is genetically heterogeneous with convergent symptomatology, suggesting common dysregulated pathways. In this study, we analyzed brain transcriptional changes in five mouse models of Pitt-Hopkins syndrome (PTHS),...
7.
Chua G, Wassarman K, Sun H, Alp J, Jarczyk E, Kuzio N, et al.
ACS Med Chem Lett . 2019 Feb; 10(2):180-185. PMID: 30783500
DNA methylation is known as the epigenetic mark for its critical role in regulating local gene transcription. Changes in the landscape of DNA methylation across the genome occur during cellular...
8.
Bales K, Ianov L, Kennedy A, Sweatt J, Gross A
Mol Vis . 2018 Feb; 24:153-164. PMID: 29463953
Purpose: Epigenetic and transcriptional mechanisms have been shown to contribute to long-lasting functional changes in adult neurons. The purpose of this study was to identify any such modifications in diseased...
9.
Stefanelli G, Azam A, Walters B, Brimble M, Gettens C, Bouchard-Cannon P, et al.
Cell Rep . 2018 Feb; 22(5):1124-1131. PMID: 29386101
Histone variants were recently discovered to regulate neural plasticity, with H2A.Z emerging as a memory suppressor. Using whole-genome sequencing of the mouse hippocampus, we show that basal H2A.Z occupancy is...
10.
Ianov L, Both M, Chawla M, Rani A, Kennedy A, Piras I, et al.
Front Aging Neurosci . 2017 Dec; 9:383. PMID: 29276487
The current study employed next-generation RNA sequencing to examine gene expression differences related to brain aging, cognitive decline, and hippocampal subfields. Young and aged rats were trained on a spatial...