Andrew Hesketh
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Explore the profile of Andrew Hesketh including associated specialties, affiliations and a list of published articles.
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22
Citations
271
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Recent Articles
1.
Bourne L, Hesketh A, Sharma A, Bucca G, Bush P, Staines K
Front Endocrinol (Lausanne)
. 2023 Dec;
14:1278596.
PMID: 38144567
Introduction: Chondrocytes are continuously exposed to loads placed upon them. Physiological loads are pivotal to the maintenance of articular cartilage health, while abnormal loads contribute to pathological joint degradation. Similarly,...
2.
Nikolaidis M, Hesketh A, Frangou N, Mossialos D, Van de Peer Y, Oliver S, et al.
Microb Genom
. 2023 Jun;
9(6).
PMID: 37266990
We delineate the evolutionary plasticity of the ecologically and biotechnologically important genus , by analysing the genomes of 213 species. Streptomycetes genomes demonstrate high levels of internal homology, whereas the...
3.
Saberianpour S, Melotto G, Forss R, Redhead L, Elsom J, Terrazzini N, et al.
Expert Rev Med Devices
. 2023 Feb;
20(3):163-165.
PMID: 36803232
No abstract available.
4.
Nikolaidis M, Hesketh A, Mossialos D, Iliopoulos I, Oliver S, Amoutzias G
Microorganisms
. 2022 Sep;
10(9).
PMID: 36144322
By integrating phylogenomic and comparative analyses of 1104 high-quality genome sequences, we identify the core proteins and the lineage-specific fingerprint proteins of the various evolutionary clusters (clades/groups/species) of the genus....
5.
Amoutzias G, Nikolaidis M, Hesketh A
Microorganisms
. 2022 May;
10(5).
PMID: 35630482
Throughout the entirety of human history, bacterial pathogens have played an important role and even shaped the fate of civilizations. The application of genomics within the last 27 years has...
6.
Burley T, Hesketh A, Bucca G, Kennedy E, Ladikou E, Towler B, et al.
Cancers (Basel)
. 2022 Apr;
14(7).
PMID: 35406371
The retention and re-migration of Chronic Lymphocytic Leukemia cells into cytoprotective and proliferative lymphoid niches is thought to contribute to the development of resistance, leading to subsequent disease relapse. The...
7.
Durrant L, Bucca G, Hesketh A, Moller-Levet C, Tripkovic L, Wu H, et al.
Front Immunol
. 2022 Mar;
13:790444.
PMID: 35281034
Vitamin D is best known for its role in maintaining bone health and calcium homeostasis. However, it also exerts a broad range of extra-skeletal effects on cellular physiology and on...
8.
Wang G, Kitaoka T, Crawford A, Mao Q, Hesketh A, Guppy F, et al.
Sci Rep
. 2021 Nov;
11(1):21705.
PMID: 34737331
RNA-seq has matured and become an important tool for studying RNA biology. Here we compared two RNA-seq (MGI DNBSEQ and Illumina NextSeq 500) and two microarray platforms (GeneChip Human Transcriptome...
9.
Mengozzi M, Hesketh A, Bucca G, Ghezzi P, Smith C
Mol Med
. 2020 Apr;
26(1):32.
PMID: 32272884
Background: Vitamin D deficiency increases the risk of developing multiple sclerosis (MS) but it is unclear whether vitamin D supplementation improves the clinical course of MS, and there is uncertainty...
10.
Magnowska Z, Jana B, Brochmann R, Hesketh A, Lametsch R, De Gobba C, et al.
Sci Rep
. 2019 Nov;
9(1):17834.
PMID: 31780689
We previously showed that doxycycline (DOX) and carprofen (CPF), a veterinary non-steroidal anti-inflammatory drug, have synergistic antimicrobial activity against methicillin-resistant Staphylococcus pseudintermedius (MRSP) carrying the tetracycline resistance determinant TetK. To...