Andrew G Cheetham
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Explore the profile of Andrew G Cheetham including associated specialties, affiliations and a list of published articles.
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34
Citations
1069
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Recent Articles
11.
Ma W, Cheetham A, Cui H
Nano Today
. 2016 Apr;
11(1):13-30.
PMID: 27066106
The convergence of nanoscience and drug delivery has prompted the formation of the field of nanomedicine, one that exploits the novel physicochemical and biological properties of nanostructures for improved medical...
12.
Hu Y, Lin R, Zhang P, Fern J, Cheetham A, Patel K, et al.
ACS Nano
. 2015 Dec;
10(1):880-8.
PMID: 26646791
Peptides or peptide conjugates capable of assembling into one-dimensional (1D) nanostructures have been extensively investigated over the past two decades due to their implications in human diseases and also their...
13.
Cheetham A, Keith D, Zhang P, Lin R, Su H, Cui H
Curr Cancer Drug Targets
. 2015 Dec;
16(6):489-508.
PMID: 26632435
Chemotherapeutic treatment of cancers is a challenging endeavor, hindered by poor selectivity towards tumorous tissues over healthy ones. Preferentially delivering a given drug to tumor sites necessitates the use of...
14.
Zhong M, Liu X, Shi F, Zhang L, Wang X, Cheetham A, et al.
Soft Matter
. 2015 Apr;
11(21):4235-41.
PMID: 25892460
We present a facile strategy to synthesize self-healable tough and highly stretchable hydrogels. Our design rationale for the creation of ionic cross-linked hydrogels is to graft an acrylic acid monomer...
15.
Zhang P, Cheetham A, Lock L, Li Y, Cui H
Curr Opin Biotechnol
. 2015 Feb;
34:171-9.
PMID: 25687686
Precise detection of pathologically relevant biomolecules could provide essential information on important intercellular, cellular, and subcellular events for accurate disease diagnosis and staging, thus leading to appropriate treatment recommendation. Activatable...
16.
Lin R, Zhang P, Cheetham A, Walston J, Abadir P, Cui H
Bioconjug Chem
. 2014 Dec;
26(1):71-7.
PMID: 25547808
Mitochondria are critical regulators of cellular function and survival. Delivery of therapeutic and diagnostic agents into mitochondria is a challenging task in modern pharmacology because the molecule to be delivered...
17.
Lin Y, Cheetham A, Zhang P, Ou Y, Li Y, Liu G, et al.
ACS Nano
. 2014 Nov;
8(12):12690-700.
PMID: 25415538
Mixing of oppositely charged amphiphilic molecules (catanionic mixing) offers an attractive strategy to produce morphologies different from those formed by individual molecules. We report here on the use of catanionic...
18.
Cui H, Cheetham A, Pashuck E, Stupp S
J Am Chem Soc
. 2014 Aug;
136(35):12461-8.
PMID: 25144245
The switching of two adjacent amino acids can lead to differences in how proteins fold thus affecting their function. This effect has not been extensively explored in synthetic peptides in...
19.
Chen Z, Zhang P, Cheetham A, Moon J, Moxley Jr J, Lin Y, et al.
J Control Release
. 2014 Jun;
191:123-30.
PMID: 24892976
Covalent modification of a drug with a peptide moiety has been extensively used as an effective strategy to improve the drug's therapeutic outcome. One important consideration in the design of...
20.
Cheetham A, Ou Y, Zhang P, Cui H
Chem Commun (Camb)
. 2014 Apr;
50(45):6039-42.
PMID: 24769796
We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the...