Andrew Fedoriw
Overview
Explore the profile of Andrew Fedoriw including associated specialties, affiliations and a list of published articles.
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5
Citations
251
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Recent Articles
1.
Fedoriw A, Shi L, OBrien S, Smitheman K, Wang Y, Hou J, et al.
Cancer Immunol Res
. 2022 Feb;
10(4):420-436.
PMID: 35181787
Protein arginine methyltransferases (PRMT) are a widely expressed class of enzymes responsible for catalyzing arginine methylation on numerous protein substrates. Among them, type I PRMTs are responsible for generating asymmetric...
2.
Fedoriw A, Rajapurkar S, OBrien S, Gerhart S, Mitchell L, Adams N, et al.
Cancer Cell
. 2019 Jul;
36(1):100-114.e25.
PMID: 31257072
Type I protein arginine methyltransferases (PRMTs) catalyze asymmetric dimethylation of arginines on proteins. Type I PRMTs and their substrates have been implicated in human cancers, suggesting inhibition of type I...
3.
Yang Y, Poe J, Yang L, Fedoriw A, Desai S, Magnuson T, et al.
Nucleic Acids Res
. 2016 Feb;
44(9):4174-88.
PMID: 26883629
In cultured cancer cells the E3 ubiquitin ligase Rad18 activates Trans-Lesion Synthesis (TLS) and the Fanconi Anemia (FA) pathway. However, physiological roles of Rad18 in DNA damage tolerance and carcinogenesis...
4.
Fedoriw A, Mugford J, Magnuson T
Cold Spring Harb Perspect Biol
. 2012 Jun;
4(7):a008136.
PMID: 22687277
Epigenetic mechanisms are extensively utilized during mammalian development. Specific patterns of gene expression are established during cell fate decisions, maintained as differentiation progresses, and often augmented as more specialized cell...
5.
Wan L, Pan H, Hannenhalli S, Cheng Y, Ma J, Fedoriw A, et al.
Development
. 2008 Jul;
135(16):2729-38.
PMID: 18614575
CTCF is a multifunctional nuclear factor involved in epigenetic regulation. Despite recent advances that include the systematic discovery of CTCF-binding sites throughout the mammalian genome, the in vivo roles of...