Andrew F Teich
Overview
Explore the profile of Andrew F Teich including associated specialties, affiliations and a list of published articles.
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70
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1960
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Recent Articles
1.
Bhattarai P, Yilmaz E, Cakir E, Korkmaz H, Lee A, Ma Y, et al.
bioRxiv
. 2025 Feb;
PMID: 39975303
Graphical Abstract: Accessibility Text: This image illustrates the effects of different APOE isoforms (ApoE-ε3 and ApoE-ε4) on blood-brain barrier (BBB) integrity, focusing on the molecular interactions between astrocytes and endothelial...
2.
Tian J, Lam T, Ross S, Ciener B, Leskinen S, Sivakumar S, et al.
J Neuropathol Exp Neurol
. 2024 Dec;
84(3):236-243.
PMID: 39715490
Human brain tissue studies have used a range of metrics to assess RNA quality but there are few large-scale cross-comparisons of presequencing quality metrics with RNA-seq quality. We analyzed how...
3.
Tuddenham J, Fujita M, Khairallah A, Harbison C, Flowers X, Coronas-Samano G, et al.
bioRxiv
. 2024 Nov;
PMID: 39605399
Development of therapeutic approaches that target specific microglia responses in amyotrophic lateral sclerosis (ALS) is crucial due to the involvement of microglia in ALS progression. Our study identifies the predominant...
4.
Roy N, Haq I, Ngo J, Bennett D, Teich A, De Jager P, et al.
Acta Neuropathol
. 2024 Nov;
148(1):75.
PMID: 39604588
Aberrant activity of the retrotransposable element long interspersed nuclear element-1 (LINE-1) has been hypothesized to contribute to cellular dysfunction in age-related disorders, including late-onset Alzheimer's disease (LOAD). However, whether LINE-1...
5.
Lam T, Ross S, Ciener B, Xiao H, Flaherty D, Lee A, et al.
medRxiv
. 2024 Nov;
PMID: 39484271
In recent years, multiple groups have shown that what is currently thought of as "Alzheimer's Disease" (AD) may be usefully viewed as several related disease subtypes. As these efforts have...
6.
Tian J, Lam T, Ross S, Ciener B, Leskinen S, Sivakumar S, et al.
bioRxiv
. 2024 Oct;
PMID: 39464020
Human brain tissue studies have historically used a range of metrics to assess RNA quality. However, few large-scale cross-comparisons of pre-sequencing quality metrics with RNA-seq quality have been published. Here,...
7.
Tuddenham J, Taga M, Haage V, Marshe V, Roostaei T, White C, et al.
Nat Neurosci
. 2024 Oct;
27(12):2521-2537.
PMID: 39406950
Human microglia play a pivotal role in neurological diseases, but we still have an incomplete understanding of microglial heterogeneity, which limits the development of targeted therapies directly modulating their state...
8.
Ghandian S, Albarghouthi L, Nava K, Sharma S, Minaud L, Beckett L, et al.
bioRxiv
. 2024 Oct;
PMID: 39386601
Accumulation of abnormal tau protein into neurofibrillary tangles (NFTs) is a pathologic hallmark of Alzheimer disease (AD). Accurate detection of NFTs in tissue samples can reveal relationships with clinical, demographic,...
9.
Tayran H, Yilmaz E, Bhattarai P, Min Y, Wang X, Ma Y, et al.
Cell Genom
. 2024 Aug;
4(9):100642.
PMID: 39216475
Genetic variants in ABCA7, an Alzheimer's disease (AD)-associated gene, elevate AD risk, yet its functional relevance to the etiology is unclear. We generated a CRISPR-Cas9-mediated abca7 knockout zebrafish to explore...
10.
Reddy J, Heath L, Linden A, Allen M, de Paiva Lopes K, Seifar F, et al.
Alzheimers Dement
. 2024 Aug;
20(10):7174-7192.
PMID: 39215503
Introduction: Multi-omics studies in Alzheimer's disease (AD) revealed many potential disease pathways and therapeutic targets. Despite their promise of precision medicine, these studies lacked Black Americans (BA) and Latin Americans...