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Andrew Currie

Explore the profile of Andrew Currie including associated specialties, affiliations and a list of published articles. Areas
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Articles 74
Citations 1671
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Recent Articles
21.
Hibbert J, Strunk T, Nathan E, Prosser A, Doherty D, Simmer K, et al.
PLoS One . 2022 Mar; 17(3):e0264768. PMID: 35235604
Background: Composition of leukocyte populations in the first month of life remains incompletely characterised, particularly in preterm infants who go on to develop late-onset sepsis (LOS). Aim: To characterise and...
22.
Hibbert J, Armstrong N, Granland C, Ng S, Simmer K, Richmond P, et al.
Acta Paediatr . 2021 Jun; 110(11):3011-3013. PMID: 34091943
Preterm infants are particularly susceptible to bacterial late-onset sepsis (LOS). Diagnosis by blood culture and inflammatory markers have sub-optimal sensitivity and specificity and prolonged reporting times. There is an urgent...
23.
Litton E, Currie A, Raby E
Intensive Care Med . 2021 May; 47(8):924-925. PMID: 34014376
No abstract available.
24.
Litton E, Anstey M, Broadhurst D, Chapman A, Currie A, Ferrier J, et al.
Intensive Care Med . 2021 Feb; 47(3):307-315. PMID: 33566129
Purpose: In adults requiring treatment in an intensive care unit, probiotic therapy using Lactobacillus plantarum 299v may reduce nosocomial infection. The aim of this study was to determine whether early...
25.
Annamalay A, Abbott S, Khoo S, Hibbert J, Bizzintino J, Zhang G, et al.
J Med Virol . 2020 Dec; 93(6):3647-3655. PMID: 33314189
Altered host immune responses are considered to play a key role in the pathogenesis of acute lower respiratory infections (ALRI). The existing literature on cytokine responses in ALRI is largely...
26.
Strunk T, Hibbert J, Doherty D, Nathan E, Simmer K, Patole S, et al.
Neonatology . 2020 Aug; 117(5):606-611. PMID: 32862184
Background: Preterm infants are at a high risk of developing late-onset sepsis (LOS). Lactoferrin is one of the most abundant endogenous antimicrobial proteins expressed in breast milk, stools, and blood,...
27.
Litton E, Anstey M, Broadhurst D, Chapman A, Currie A, Ferrier J, et al.
BMJ Open . 2020 Jun; 10(6):e035930. PMID: 32565465
Introduction: The effect of early and sustained administration of daily probiotic therapy on patients admitted to the intensive care unit (ICU) remains uncertain. Methods And Analysis: The Restoration Of gut...
28.
Ng S, Strunk T, Lee A, Gill E, Falsafi R, Woodman T, et al.
PLoS One . 2020 Jun; 15(6):e0233841. PMID: 32479514
Background: Host immune responses during late-onset sepsis (LOS) in very preterm infants are poorly characterised due to a complex and dynamic pathophysiology and challenges in working with small available blood...
29.
Hibbert J, Strunk T, Simmer K, Richmond P, Burgner D, Currie A
PLoS One . 2020 May; 15(5):e0232933. PMID: 32407417
Introduction: Deficiencies in innate immune responses may contribute to the increased susceptibility to infection in preterm infants. In vivo cytokine profiles in response to sepsis in very preterm infants are...
30.
Strunk T, Hibbert J, Doherty D, Nathan E, Simmer K, Richmond P, et al.
Clin Infect Dis . 2020 Jan; 72(2):271-278. PMID: 31960030
Background: Late-onset sepsis (LOS) with Staphylococcus epidermidis is common in preterm infants, but the immunological mechanisms underlying heightened susceptibility are poorly understood. Our aim is to characterize the ontogeny of...