Andrew Clear
Overview
Explore the profile of Andrew Clear including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
1624
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0
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Recent Articles
1.
Kumar E, Korfi K, Bewicke-Copley F, Close K, Heward J, Witzig T, et al.
Br J Haematol
. 2024 Aug;
205(5):1804-1809.
PMID: 39188028
Despite the clinical and molecular heterogeneity of follicular lymphoma (FL), there remains a lack of biomarker-directed therapeutic approaches in routine clinical practice, with the notable exception of the EZH2 inhibitor...
2.
Natkunam Y, de Jong D, Farinha P, Gaulard P, Klapper W, Rosenwald A, et al.
Histopathology
. 2023 Feb;
82(7):1105-1111.
PMID: 36849712
Aims: Subclassification of large B cell lymphoma (LBCL) is challenging due to the overlap in histopathological, immunophenotypical and genetic data. In particular, the criteria to separate diffuse large B cell...
3.
Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, et al.
Blood Adv
. 2022 Aug;
7(5):845-855.
PMID: 35947123
Despite the effectiveness of immuno-chemotherapy, 40% of patients with diffuse large B-cell lymphoma (DLBCL) experience relapse or refractory disease. Longitudinal studies have previously focused on the mutational landscape of relapse...
4.
Taylor J, Truelove E, Clear A, Calaminici M, Gribben J
Haematologica
. 2022 Jul;
108(4):1068-1082.
PMID: 35833296
Classical Hodgkin lymphoma (CHL) is unusually sensitive to PD1 inhibition and PDL1 is highly expressed on CHL cells and in the tumor microenvironment. This could be interpreted as evidence of...
5.
Delvecchio F, Fincham R, Spear S, Clear A, Roy-Luzarraga M, Balkwill F, et al.
Cell Mol Gastroenterol Hepatol
. 2021 Jul;
12(5):1543-1565.
PMID: 34252585
Background And Aims: The presence of tertiary lymphoid structures (TLSs) may confer survival benefit to patients with pancreatic ductal adenocarcinoma (PDAC), in an otherwise immunologically inert malignancy. Yet, the precise...
6.
Heward J, Konali L, DAvola A, Close K, Yeomans A, Philpott M, et al.
Blood
. 2021 Mar;
138(5):370-381.
PMID: 33786580
Loss-of-function mutations in KMT2D are a striking feature of germinal center (GC) lymphomas, resulting in decreased histone 3 lysine 4 (H3K4) methylation and altered gene expression. We hypothesized that inhibition...
7.
Roy-Luzarraga M, Abdel-Fatah T, Reynolds L, Clear A, Taylor J, Gribben J, et al.
JAMA Netw Open
. 2020 Oct;
3(10):e2019304.
PMID: 33107920
Importance: Determining the risk of relapse after neoadjuvant chemotherapy in patients with locally advanced breast cancer is required to offer alternative therapeutic strategies. Objective: To examine whether endothelial cell phosphorylated-focal...
8.
Ball J, Clear A, Aries J, Charrot S, Besley C, Mee M, et al.
Blood
. 2020 Sep;
137(5):702-717.
PMID: 32905596
Gastrointestinal (GI) graft-versus-host disease (GVHD) is a major barrier in allogeneic hematopoietic stem cell transplantation (allo-HSCT). The metabolite retinoic acid (RA) potentiates GI-GVHD in mice via alloreactive T cells expressing...
9.
Wong P, Munoz-Felix J, Hijazi M, Kim H, Robinson S, de Luxan-Delgado B, et al.
Cell
. 2020 May;
181(6):1346-1363.e21.
PMID: 32473126
Enhanced blood vessel (BV) formation is thought to drive tumor growth through elevated nutrient delivery. However, this observation has overlooked potential roles for mural cells in directly affecting tumor growth...
10.
Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkamper A, et al.
Cell Rep
. 2019 May;
27(5):1461-1471.e4.
PMID: 31042473
B cell lymphoma-6 (BCL6) is highly expressed in germinal center B cells, but how its expression is maintained is still not completely clear. Aryl hydrocarbon receptor interacting protein (AIP) is...