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Andres Vargas-Toscano

Explore the profile of Andres Vargas-Toscano including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 47
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Recent Articles
1.
Du R, Sanin A, Shi W, Huang B, Nickel A, Vargas-Toscano A, et al.
Front Pharmacol . 2024 Oct; 15:1468920. PMID: 39386028
Glioblastoma (GBM) is the most commonly occurring and most aggressive primary brain tumor. Transcriptomics-based tumor subtype classification has established the mesenchymal lineage of GBM (MES-GBM) as cancers with particular aggressive...
2.
Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjornsson M, et al.
Nat Commun . 2024 May; 15(1):4083. PMID: 38744825
Energetic stress compels cells to evolve adaptive mechanisms to adjust their metabolism. Inhibition of mTOR kinase complex 1 (mTORC1) is essential for cell survival during glucose starvation. How mTORC1 controls...
3.
Vargas-Toscano A, Janiak C, Sabel M, Kahlert U
J Pers Med . 2021 Sep; 11(9). PMID: 34575669
Efficient transdisciplinary cooperation promotes the rapid discovery and clinical application of new technologies, especially in the competitive sector of oncology. In this review, written from a clinical-scientist point of view,...
4.
Vargas-Toscano A, Nickel A, Li G, Kamp M, Muhammad S, Leprivier G, et al.
Cancers (Basel) . 2020 Dec; 12(12). PMID: 33371210
Glioblastoma (GBM) is a lethal disease with limited clinical treatment options available. Recently, a new inhibitor targeting the prominent cancer signaling pathway mTOR was discovered (Rapalink-1), but its therapeutic potential...
5.
Vargas-Toscano A, Khan D, Nickel A, Hewera M, Kamp M, Fischer I, et al.
CNS Oncol . 2020 May; 9(2):CNS58. PMID: 32462934
Glioblastoma is a heterogeneous lethal disease, regulated by a stem-cell hierarchy and the neurotransmitter microenvironment. The identification of chemotherapies targeting individual cancer stem cells is a clinical need. A robotic...
6.
Benedetti-Isaac J, Torres-Zambrano M, Vargas-Toscano A, Perea-Castro E, Alcala-Cerra G, Furlanetti L, et al.
Epilepsia . 2015 Jul; 56(7):1152-61. PMID: 26146753
Objectives: The aim of this study was to analyze the impact of deep brain stimulation (DBS) of the posteromedial hypothalamus (pHyp) on seizure frequency in patients with drug-resistant epilepsy (DRE)...